Extracellular granzyme K enhances PD-L1 transcription and stability via F2RL1 activation to facilitate tumor immune evasion in lung adenocarcinoma.
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| Title: | Extracellular granzyme K enhances PD-L1 transcription and stability via F2RL1 activation to facilitate tumor immune evasion in lung adenocarcinoma. |
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| Authors: | Feng HM; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China.; Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China., Zhao Y; Department of Radiotherapy, Gansu Provincial People's Hospital, Lanzhou, China., Zhai KR; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China., Li B; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China leebin@lzu.edu.cn.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China., Song TN; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China., Meng YQ; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China., Huang HR; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China.; Department of Pulmonary and Critical Care Medicine, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China., Li Z; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China.; Department of Thoracic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Cui BQ; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China., Yang N; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China., Su ZP; Department of Thoracic Surgery, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China. |
| Source: | Journal for immunotherapy of cancer [J Immunother Cancer] 2026 Jan 12; Vol. 14 (1). Date of Electronic Publication: 2026 Jan 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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