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Hepatic loss of AATF attenuates MASH by suppressing AKT-mTORC1 signaling and reprogramming lipid metabolism.

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Title: Hepatic loss of AATF attenuates MASH by suppressing AKT-mTORC1 signaling and reprogramming lipid metabolism.
Authors: Srinivas AN; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Suresh D; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Anirvan P; Department of Translational Research, Kalinga Gastroenterology Foundation, Cuttack, Odisha, India., Moorthy M; TheraCUES Innovations Pvt. Ltd, Bangalore, India., Ramaswamy G; TheraCUES Innovations Pvt. Ltd, Bangalore, India., Nataraj SM; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Santhekadur PK; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Suvarna D; Department of Gastroenterology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, 570015, India., Singh SP; Department of Translational Research, Kalinga Gastroenterology Foundation, Cuttack, Odisha, India., Kumar DP; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India. divyapk243@gmail.com.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 Jan 13; Vol. 32 (1), pp. 19. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hepatic loss of AATF attenuates MASH by suppressing AKT-mTORC1 signaling and reprogramming lipid metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Srinivas+AN%22">Srinivas AN</searchLink>; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Suresh+D%22">Suresh D</searchLink>; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Anirvan+P%22">Anirvan P</searchLink>; Department of Translational Research, Kalinga Gastroenterology Foundation, Cuttack, Odisha, India.<br /><searchLink fieldCode="AU" term="%22Moorthy+M%22">Moorthy M</searchLink>; TheraCUES Innovations Pvt. Ltd, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Ramaswamy+G%22">Ramaswamy G</searchLink>; TheraCUES Innovations Pvt. Ltd, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Nataraj+SM%22">Nataraj SM</searchLink>; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Santhekadur+PK%22">Santhekadur PK</searchLink>; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Suvarna+D%22">Suvarna D</searchLink>; Department of Gastroenterology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, 570015, India.<br /><searchLink fieldCode="AU" term="%22Singh+SP%22">Singh SP</searchLink>; Department of Translational Research, Kalinga Gastroenterology Foundation, Cuttack, Odisha, India.<br /><searchLink fieldCode="AU" term="%22Kumar+DP%22">Kumar DP</searchLink>; Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India. divyapk243@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%229501023%22">Molecular medicine (Cambridge, Mass.)</searchLink> [Mol Med] 2026 Jan 13; Vol. 32 (1), pp. 19. <i>Date of Electronic Publication: </i>2026 Jan 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9501023 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-3658 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210761551%22">10761551 </searchLink><i>NLM ISO Abbreviation: </i>Mol Med <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan 13
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