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Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.

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Title: Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.
Authors: Lin C; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan., Tsai ML; Department of Food Science, National Taiwan Ocean University, Keelung, 20224, Taiwan, ROC., Chao HY; Department of Food Science, National Taiwan Ocean University, Keelung, 20224, Taiwan, ROC., Cheng TM; The PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan., Shih CM; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan., Wu ATH; The PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan., Cheng CH; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan., Hsiao CY; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan., Lu HY; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. hsinyinglu110@tmu.edu.tw.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. hsinyinglu110@tmu.edu.tw.; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, 11696, Taiwan. hsinyinglu110@tmu.edu.tw., Shih CC; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. ccshih0603@tmu.edu.tw.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. ccshih0603@tmu.edu.tw.; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, 11696, Taiwan. ccshih0603@tmu.edu.tw., Mi FL; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Jan 13; Vol. 24 (1), pp. 41. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.
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  Data: <searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+ML%22">Tsai ML</searchLink>; Department of Food Science, National Taiwan Ocean University, Keelung, 20224, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chao+HY%22">Chao HY</searchLink>; Department of Food Science, National Taiwan Ocean University, Keelung, 20224, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Cheng+TM%22">Cheng TM</searchLink>; The PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+CM%22">Shih CM</searchLink>; Division of Cardiology and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+ATH%22">Wu ATH</searchLink>; The PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+CH%22">Cheng CH</searchLink>; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsiao+CY%22">Hsiao CY</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lu+HY%22">Lu HY</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. hsinyinglu110@tmu.edu.tw.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. hsinyinglu110@tmu.edu.tw.; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, 11696, Taiwan. hsinyinglu110@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Shih+CC%22">Shih CC</searchLink>; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. ccshih0603@tmu.edu.tw.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. ccshih0603@tmu.edu.tw.; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, 11696, Taiwan. ccshih0603@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Mi+FL%22">Mi FL</searchLink>; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.; Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan. flmi530326@tmu.edu.tw.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12951-025-04012-7
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        Text: English
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        StartPage: 41
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      – TitleFull: Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.
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            – D: 13
              M: 01
              Text: 2026 Jan 13
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