How are patient-reported pain outcomes associated with biomarker and structural pathology subtypes in knee osteoarthritis? An explorative evaluation in the IMI-APPROACH cohort.

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Title: How are patient-reported pain outcomes associated with biomarker and structural pathology subtypes in knee osteoarthritis? An explorative evaluation in the IMI-APPROACH cohort.
Authors: Jansen MP; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Mastbergen SC; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Wirth W; Research Program for Musculoskeletal Imaging, Center for Anatomy and Cell Biology & Ludwig Boltzmann Institute for Arthritis and Rehabilitation (LBIAR), Paracelsus Medical University, Salzburg, Austria.; Chondrometrics GmbH, Freilassing, Germany., Roemer FW; Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA.; Department of Radiology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Bacardit J; Interdisciplinary Computing and Complex BioSystems (ICOS) Research Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom., Bay-Jensen AC; ImmunoScience, Nordic Bioscience, Herlev, Denmark., Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Blanco FJ; Grupo de Investigación de Reumatología (GIR), INIBIC - Complejo Hospitalario Universitario de A Coruña, SERGAS, Centro de Investigación CICA, Departamento de Fisioterapia y Medicina, Universidad de A Coruña, A Coruña, Spain., Haugen IK; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Berenbaum F; Department of Rheumatology, AP-HP Saint-Antoine Hospital, Paris, France.; Sorbonne University, INSERM CRSA, Paris, France., Eijkelkamp N; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Jarraya M; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Source: Osteoarthritis and cartilage open [Osteoarthr Cartil Open] 2025 Dec 11; Vol. 8 (1), pp. 100726. Date of Electronic Publication: 2025 Dec 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101767068 Publication Model: eCollection Cited Medium: Internet ISSN: 2665-9131 (Electronic) Linking ISSN: 26659131 NLM ISO Abbreviation: Osteoarthr Cartil Open Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Jansen+MP%22">Jansen MP</searchLink>; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mastbergen+SC%22">Mastbergen SC</searchLink>; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wirth+W%22">Wirth W</searchLink>; Research Program for Musculoskeletal Imaging, Center for Anatomy and Cell Biology & Ludwig Boltzmann Institute for Arthritis and Rehabilitation (LBIAR), Paracelsus Medical University, Salzburg, Austria.; Chondrometrics GmbH, Freilassing, Germany.<br /><searchLink fieldCode="AU" term="%22Roemer+FW%22">Roemer FW</searchLink>; Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA.; Department of Radiology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Bacardit+J%22">Bacardit J</searchLink>; Interdisciplinary Computing and Complex BioSystems (ICOS) Research Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bay-Jensen+AC%22">Bay-Jensen AC</searchLink>; ImmunoScience, Nordic Bioscience, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Kloppenburg+M%22">Kloppenburg M</searchLink>; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Blanco+FJ%22">Blanco FJ</searchLink>; Grupo de Investigación de Reumatología (GIR), INIBIC - Complejo Hospitalario Universitario de A Coruña, SERGAS, Centro de Investigación CICA, Departamento de Fisioterapia y Medicina, Universidad de A Coruña, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Haugen+IK%22">Haugen IK</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Berenbaum+F%22">Berenbaum F</searchLink>; Department of Rheumatology, AP-HP Saint-Antoine Hospital, Paris, France.; Sorbonne University, INSERM CRSA, Paris, France.<br /><searchLink fieldCode="AU" term="%22Eijkelkamp+N%22">Eijkelkamp N</searchLink>; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jarraya+M%22">Jarraya M</searchLink>; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101767068 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2665-9131 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226659131%22">26659131 </searchLink><i>NLM ISO Abbreviation: </i>Osteoarthr Cartil Open <i>Subsets: </i>PubMed not MEDLINE
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