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Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.

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Title: Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.
Authors: Turcotte EA; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Kim K; Department of Microbiology, Harvard Medical School, Boston, MA 02115.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111., Eislmayr KD; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Goers L; Department of Microbiology, Harvard Medical School, Boston, MA 02115., Mitchell PS; Department of Microbiology, University of Washington, Seattle, WA 98109.; HHMI, University of Washington, Seattle, WA 98109., Lesser CF; Department of Microbiology, Harvard Medical School, Boston, MA 02115.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111.; Stuart B Levy Center for the Integrated Management of Antimicrobial Resistance, Tufts University, Boston, MA 02111.; Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02115., Vance RE; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; Center for Emerging and Neglected Disease, University of California, Berkeley, CA 94720.; Cancer Research Laboratory, University of California, Berkeley, CA 94720.; HHMI, University of California, Berkeley, CA 94720.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jan 20; Vol. 123 (3), pp. e2510950123. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.
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  Data: <searchLink fieldCode="AU" term="%22Turcotte+EA%22">Turcotte EA</searchLink>; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Department of Microbiology, Harvard Medical School, Boston, MA 02115.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111.<br /><searchLink fieldCode="AU" term="%22Eislmayr+KD%22">Eislmayr KD</searchLink>; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.<br /><searchLink fieldCode="AU" term="%22Goers+L%22">Goers L</searchLink>; Department of Microbiology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Mitchell+PS%22">Mitchell PS</searchLink>; Department of Microbiology, University of Washington, Seattle, WA 98109.; HHMI, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Lesser+CF%22">Lesser CF</searchLink>; Department of Microbiology, Harvard Medical School, Boston, MA 02115.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111.; Stuart B Levy Center for the Integrated Management of Antimicrobial Resistance, Tufts University, Boston, MA 02111.; Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Vance+RE%22">Vance RE</searchLink>; Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; Center for Emerging and Neglected Disease, University of California, Berkeley, CA 94720.; Cancer Research Laboratory, University of California, Berkeley, CA 94720.; HHMI, University of California, Berkeley, CA 94720.
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