Impact of enduring risk factors on efficacy and safety of extended anticoagulation for provoked venous thromboembolism: Post-hoc analysis of the HI-PRO trial.

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Title: Impact of enduring risk factors on efficacy and safety of extended anticoagulation for provoked venous thromboembolism: Post-hoc analysis of the HI-PRO trial.
Authors: Pfeferman M; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Rashedi S; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Pandey AK; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Krishnathasan D; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Khairani CD; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bejjani A; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Morrison RH; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hogan H; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lou J; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Fanikos J; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pharmacy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Porio N; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Rosenbaum L; Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Sobieszczyk P; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lan Z; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Center for Clinical Investigation, Harvard Medical School, Boston, MA, USA., Gerhard-Herman M; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Campia U; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Goldhaber SZ; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bikdeli B; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Yale New Haven Hospital (YNHH), Yale Center for Outcomes Research and Evaluation (CORE), New Haven, CT, USA., Piazza G; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: gpiazza@bwh.harvard.edu.
Corporate Authors: HI-PRO Trial Investigators
Source: Thrombosis research [Thromb Res] 2026 Feb; Vol. 258, pp. 109588. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Letter
Journal Info: Publisher: Pergamon Press Country of Publication: United States NLM ID: 0326377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2472 (Electronic) Linking ISSN: 00493848 NLM ISO Abbreviation: Thromb Res Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1879-2472
DOI:10.1016/j.thromres.2026.109588