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Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy.

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Title: Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy.
Authors: Li CL; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Li FM; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Feng KK; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Hu YS; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Tu YF; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Tian SC; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China., Liu ZH; Department of Oncology, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, Fujian 350001, China. Electronic address: liuzhenhua6909@163.com., Shao JW; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China. Electronic address: shaojingwei@fzu.edu.cn.
Source: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2026 May; Vol. 261, pp. 115420. Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4367 (Electronic) Linking ISSN: 09277765 NLM ISO Abbreviation: Colloids Surf B Biointerfaces Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy.
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  Data: <searchLink fieldCode="AU" term="%22Li+CL%22">Li CL</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Li+FM%22">Li FM</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Feng+KK%22">Feng KK</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Hu+YS%22">Hu YS</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Tu+YF%22">Tu YF</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Tian+SC%22">Tian SC</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.<br /><searchLink fieldCode="AU" term="%22Liu+ZH%22">Liu ZH</searchLink>; Department of Oncology, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, Fujian 350001, China. Electronic address: liuzhenhua6909@163.com.<br /><searchLink fieldCode="AU" term="%22Shao+JW%22">Shao JW</searchLink>; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China. Electronic address: shaojingwei@fzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229315133%22">Colloids and surfaces. B, Biointerfaces</searchLink> [Colloids Surf B Biointerfaces] 2026 May; Vol. 261, pp. 115420. <i>Date of Electronic Publication: </i>2026 Jan 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9315133 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4367 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209277765%22">09277765 </searchLink><i>NLM ISO Abbreviation: </i>Colloids Surf B Biointerfaces <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.colsurfb.2026.115420
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      – Code: eng
        Text: English
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        StartPage: 115420
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      – TitleFull: Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy.
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            NameFull: Li CL
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            NameFull: Li FM
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            NameFull: Tian SC
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            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
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              Value: 1873-4367
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              Value: 261
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            – TitleFull: Colloids and surfaces. B, Biointerfaces
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