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Starvation of leukemic cells enhances DNA damage-induced apoptosis in vitro via ROS/p38 MAPK and prevents leukemia progression in fasting xenograft mice.

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Title: Starvation of leukemic cells enhances DNA damage-induced apoptosis in vitro via ROS/p38 MAPK and prevents leukemia progression in fasting xenograft mice.
Authors: Yadav A; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Richartz N; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Bhagwat S; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Burman MM; Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway., Munthe-Kaas MC; Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway., Skålhegg BS; Department of Nutrition Research, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Wik JA; Department of Nutrition Research, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Naderi S; Department of Pharmacology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway., Blomhoff HK; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. Electronic address: h.k.blomhoff@medisin.uio.no.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Mar; Vol. 302 (3), pp. 111143. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Starvation of leukemic cells enhances DNA damage-induced apoptosis in vitro via ROS/p38 MAPK and prevents leukemia progression in fasting xenograft mice.
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  Data: <searchLink fieldCode="AU" term="%22Yadav+A%22">Yadav A</searchLink>; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Richartz+N%22">Richartz N</searchLink>; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Bhagwat+S%22">Bhagwat S</searchLink>; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Burman+MM%22">Burman MM</searchLink>; Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Munthe-Kaas+MC%22">Munthe-Kaas MC</searchLink>; Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Skålhegg+BS%22">Skålhegg BS</searchLink>; Department of Nutrition Research, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Wik+JA%22">Wik JA</searchLink>; Department of Nutrition Research, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Naderi+S%22">Naderi S</searchLink>; Department of Pharmacology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Blomhoff+HK%22">Blomhoff HK</searchLink>; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. Electronic address: h.k.blomhoff@medisin.uio.no.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2026 Mar; Vol. 302 (3), pp. 111143. <i>Date of Electronic Publication: </i>2026 Jan 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbc.2026.111143
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        Text: English
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        StartPage: 111143
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      – TitleFull: Starvation of leukemic cells enhances DNA damage-induced apoptosis in vitro via ROS/p38 MAPK and prevents leukemia progression in fasting xenograft mice.
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              Text: 2026 Mar
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