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6-Phosphogluconate dehydrogenase promotes mitochondrial fusion and immune suppression in tumor-associated monocytic suppressor cells.

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Title: 6-Phosphogluconate dehydrogenase promotes mitochondrial fusion and immune suppression in tumor-associated monocytic suppressor cells.
Authors: Daneshmandi S; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Saeed.daneshmandi@roswellpark.org.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Saeed.daneshmandi@roswellpark.org., Yan Q; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Gomez EC; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Choi JE; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Katsuta E; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Institute of Science Tokyo, Tokyo, Japan., Gharib E; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Singh PK; Department of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Higashi RM; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA., Lane AN; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA., Fan TW; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA., Wang J; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Repasky EA; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., McCarthy PL; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Mohammadpour H; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Hemn.mohammadpour@roswellpark.org.
Source: Nature communications [Nat Commun] 2026 Jan 14; Vol. 17 (1), pp. 229. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 6-Phosphogluconate dehydrogenase promotes mitochondrial fusion and immune suppression in tumor-associated monocytic suppressor cells.
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  Data: <searchLink fieldCode="AU" term="%22Daneshmandi+S%22">Daneshmandi S</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Saeed.daneshmandi@roswellpark.org.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Saeed.daneshmandi@roswellpark.org.<br /><searchLink fieldCode="AU" term="%22Yan+Q%22">Yan Q</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gomez+EC%22">Gomez EC</searchLink>; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Choi+JE%22">Choi JE</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Katsuta+E%22">Katsuta E</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Gharib+E%22">Gharib E</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Singh+PK%22">Singh PK</searchLink>; Department of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Higashi+RM%22">Higashi RM</searchLink>; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Lane+AN%22">Lane AN</searchLink>; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Fan+TW%22">Fan TW</searchLink>; Department of Toxicology and Cancer Biology, Markey Cancer Center, Center for Environmental and Systems Biochemistry (CESB), Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Repasky+EA%22">Repasky EA</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22McCarthy+PL%22">McCarthy PL</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mohammadpour+H%22">Mohammadpour H</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Hemn.mohammadpour@roswellpark.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Jan 14; Vol. 17 (1), pp. 229. <i>Date of Electronic Publication: </i>2026 Jan 14.
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