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G protein-dependent dopamine D2 receptor signaling mediates cocaine-primed reinstatement.

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Title: G protein-dependent dopamine D2 receptor signaling mediates cocaine-primed reinstatement.
Authors: Li HB; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Liu YH; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Liu H; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Li Y; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Le QM; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Wang FF; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China., Ma L; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China. lanma@fudan.edu.cn.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China. lanma@fudan.edu.cn., Liu X; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China. xingliu@fudan.edu.cn.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China. xingliu@fudan.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 May; Vol. 47 (5), pp. 1117-1131. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: G protein-dependent dopamine D2 receptor signaling mediates cocaine-primed reinstatement.
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  Data: <searchLink fieldCode="AU" term="%22Li+HB%22">Li HB</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Liu+YH%22">Liu YH</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Le+QM%22">Le QM</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Wang+FF%22">Wang FF</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China. lanma@fudan.edu.cn.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China. lanma@fudan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Pharmacology Research Center, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200032, China. xingliu@fudan.edu.cn.; Research Unit of Addiction Memory, Chinese Academy of Medical Sciences (2021RU009), Shanghai, 200032, China. xingliu@fudan.edu.cn.
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        Value: 10.1038/s41401-025-01700-w
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              Text: 2026 May
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