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Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions.

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Title: Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions.
Authors: Meduri GU; Department of Medicine and Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Lannini S; Department of Medicine, University of Udine, Azienda Sanitaria Friuli Centrale Clinica di Malattie Infettive Udine, Italy., Smit JM; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.; Pattern Recognition & Bioinformatics Group, Delft University of Technology, Delft, The Netherlands.
Source: Seminars in respiratory and critical care medicine [Semin Respir Crit Care Med] 2026 Feb; Vol. 47 (1), pp. 140-160. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article; Review
Journal Info: Publisher: Thieme Medical Publishers Country of Publication: United States NLM ID: 9431858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-9048 (Electronic) Linking ISSN: 10693424 NLM ISO Abbreviation: Semin Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions.
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  Data: <searchLink fieldCode="AU" term="%22Meduri+GU%22">Meduri GU</searchLink>; Department of Medicine and Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, United States.<br /><searchLink fieldCode="AU" term="%22Lannini+S%22">Lannini S</searchLink>; Department of Medicine, University of Udine, Azienda Sanitaria Friuli Centrale Clinica di Malattie Infettive Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Smit+JM%22">Smit JM</searchLink>; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.; Pattern Recognition & Bioinformatics Group, Delft University of Technology, Delft, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%229431858%22">Seminars in respiratory and critical care medicine</searchLink> [Semin Respir Crit Care Med] 2026 Feb; Vol. 47 (1), pp. 140-160. <i>Date of Electronic Publication: </i>2026 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Thieme+Medical+Publishers%22">Thieme Medical Publishers </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9431858 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-9048 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210693424%22">10693424 </searchLink><i>NLM ISO Abbreviation: </i>Semin Respir Crit Care Med <i>Subsets: </i>MEDLINE
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        Value: 10.1055/a-2762-8278
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        Text: English
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        StartPage: 140
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      – TitleFull: Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions.
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              Text: 2026 Feb
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              Y: 2026
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