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Running exercise mitigates amyloidosis in 5xFAD mice by improving the structure and function of the meningeal lymphatic system.

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Title: Running exercise mitigates amyloidosis in 5xFAD mice by improving the structure and function of the meningeal lymphatic system.
Authors: Mee-Inta O; Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chiang YY; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan., Tsai SF; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Yang TM; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Zhao ZW; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Wang TF; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Wu HY; Instrumentation Center, National Taiwan University, Taipei, Taiwan., Hsiung CW; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Liao PC; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Lee HT; Institute of Anatomy and Cell Biology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Huang CC; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan. cchuang@mail.ncku.edu.tw.; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan. cchuang@mail.ncku.edu.tw., Wu PC; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Institute of Oral Medicine and Department of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Center of Applied Nanomedicine, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com., Kuo YM; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. kuoym@mail.ncku.edu.tw.; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan. kuoym@mail.ncku.edu.tw.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Jan 15; Vol. 14 (1). Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Running exercise mitigates amyloidosis in 5xFAD mice by improving the structure and function of the meningeal lymphatic system.
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  Data: <searchLink fieldCode="AU" term="%22Mee-Inta+O%22">Mee-Inta O</searchLink>; Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+YY%22">Chiang YY</searchLink>; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+SF%22">Tsai SF</searchLink>; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+TM%22">Yang TM</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Zhao+ZW%22">Zhao ZW</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+TF%22">Wang TF</searchLink>; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+HY%22">Wu HY</searchLink>; Instrumentation Center, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsiung+CW%22">Hsiung CW</searchLink>; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+PC%22">Liao PC</searchLink>; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+HT%22">Lee HT</searchLink>; Institute of Anatomy and Cell Biology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CC%22">Huang CC</searchLink>; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan. cchuang@mail.ncku.edu.tw.; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan. cchuang@mail.ncku.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wu+PC%22">Wu PC</searchLink>; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Institute of Oral Medicine and Department of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.; Center of Applied Nanomedicine, National Cheng Kung University, Tainan, Taiwan. wbcxyz@gmail.com.<br /><searchLink fieldCode="AU" term="%22Kuo+YM%22">Kuo YM</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. kuoym@mail.ncku.edu.tw.; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan. kuoym@mail.ncku.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101610673%22">Acta neuropathologica communications</searchLink> [Acta Neuropathol Commun] 2026 Jan 15; Vol. 14 (1). <i>Date of Electronic Publication: </i>2026 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101610673 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-5960 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220515960%22">20515960 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol Commun <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s40478-025-02218-2
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              Text: 2026 Jan 15
              Type: published
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