Randomized, Double-Blind, Active-Controlled, Parallel, Phase 3 Clinical Trial for Evaluating the Efficacy and Safety of Zastaprazan in Patients with Gastric Ulcers.

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Title: Randomized, Double-Blind, Active-Controlled, Parallel, Phase 3 Clinical Trial for Evaluating the Efficacy and Safety of Zastaprazan in Patients with Gastric Ulcers.
Authors: Park KS; Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea., Kim HS; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea., Oh JH; Department of Internal Medicine, The Catholic University of Korea Eunpyeong St. Mary's Hospital, Seoul, Korea., Chung WC; Department of Internal Medicine, The Catholic University of Korea St. Vincent's Hospital, Suwon, Korea., Choi SC; Department of Internal Medicine, Wonkwang University Hospital, Iksan, Korea., Lee SH; Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea., Kim TH; Department of Internal Medicine, The Catholic University of Korea Bucheon St. Mary's Hospital, Bucheon, Korea., Cheung DY; Department of Internal Medicine, The Catholic University of Korea Yeouido St. Mary's Hospital, Seoul, Korea., Baik GH; Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea., Kim SM; Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea., Lee HL; Department of Internal Medicine, Hanyang University Hospital, Seoul, Korea., Moon JS; Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea., Choi CW; Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National Un., Sohn C; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul, Korea., Kim KO; Department of Internal Medicine, Cancer Center, Gachon University Gil Medical Center, Incheon, Korea., Kim BW; Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea., Jung HK; Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea., Jung DH; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea., Kim SS; Department of Internal Medicine, The Catholic University of Korea Uijeongbu St. Mary's Hospital, Uijeongbu, Korea., Park MI; Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea., Lee JY; Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea., Kim GH; Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea., Moon HS; Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea., Chun H; Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea., Shim KN; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea., Shin WG; Department of Internal Medicine, Digestive Disease Center, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea., Park CH; Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea., Kim T; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea., Jung SW; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea., Kim H; Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea., Jee SR; Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea., Lee K; Department of Internal Medicine, Ajou University Hospital, Suwon, Korea., Cho YK; Department of Internal Medicine, The Catholic University of Korea Seoul St. Mary's Hospital, Seoul, Korea., Park SC; Department of Internal Medicine, Kangwon National University College of Medicine, Chuncheon, Korea., Cho J; Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea., Huh C; Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea., Kwon H; Onconic Therapeutics Inc, Seoul, Korea., Kim J; Onconic Therapeutics Inc, Seoul, Korea., Kim J; Onconic Therapeutics Inc, Seoul, Korea., Park JJ; Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
Source: Gut and liver [Gut Liver] 2026 Jul 15; Vol. 20 (4), pp. 562-574. Date of Electronic Publication: 2026 Jan 16.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III
Journal Info: Publisher: Editorial Office of Gut and Liver Country of Publication: Korea (South) NLM ID: 101316452 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-1212 (Electronic) Linking ISSN: 19762283 NLM ISO Abbreviation: Gut Liver Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Randomized, Double-Blind, Active-Controlled, Parallel, Phase 3 Clinical Trial for Evaluating the Efficacy and Safety of Zastaprazan in Patients with Gastric Ulcers.
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Department of Internal Medicine, The Catholic University of Korea Bucheon St. Mary's Hospital, Bucheon, Korea.<br /><searchLink fieldCode="AU" term="%22Cheung+DY%22">Cheung DY</searchLink>; Department of Internal Medicine, The Catholic University of Korea Yeouido St. Mary's Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Baik+GH%22">Baik GH</searchLink>; Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SM%22">Kim SM</searchLink>; Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HL%22">Lee HL</searchLink>; Department of Internal Medicine, Hanyang University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JS%22">Moon JS</searchLink>; Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+CW%22">Choi CW</searchLink>; Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National Un.<br /><searchLink fieldCode="AU" term="%22Sohn+C%22">Sohn C</searchLink>; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+KO%22">Kim KO</searchLink>; Department of Internal Medicine, Cancer Center, Gachon University Gil Medical Center, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BW%22">Kim BW</searchLink>; Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+HK%22">Jung HK</searchLink>; Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+DH%22">Jung DH</searchLink>; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SS%22">Kim SS</searchLink>; Department of Internal Medicine, The Catholic University of Korea Uijeongbu St. Mary's Hospital, Uijeongbu, Korea.<br /><searchLink fieldCode="AU" term="%22Park+MI%22">Park MI</searchLink>; Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+GH%22">Kim GH</searchLink>; Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Moon+HS%22">Moon HS</searchLink>; Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Chun+H%22">Chun H</searchLink>; Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shim+KN%22">Shim KN</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+WG%22">Shin WG</searchLink>; Department of Internal Medicine, Digestive Disease Center, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Park+CH%22">Park CH</searchLink>; Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+T%22">Kim T</searchLink>; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SW%22">Jung SW</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea.<br /><searchLink fieldCode="AU" term="%22Jee+SR%22">Jee SR</searchLink>; Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+K%22">Lee K</searchLink>; Department of Internal Medicine, Ajou University Hospital, Suwon, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YK%22">Cho YK</searchLink>; Department of Internal Medicine, The Catholic University of Korea Seoul St. Mary's Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Park+SC%22">Park SC</searchLink>; Department of Internal Medicine, Kangwon National University College of Medicine, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+J%22">Cho J</searchLink>; Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.<br /><searchLink fieldCode="AU" term="%22Huh+C%22">Huh C</searchLink>; Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+H%22">Kwon H</searchLink>; Onconic Therapeutics Inc, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Onconic Therapeutics Inc, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Onconic Therapeutics Inc, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Park+JJ%22">Park JJ</searchLink>; Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
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  Data: <searchLink fieldCode="JN" term="%22101316452%22">Gut and liver</searchLink> [Gut Liver] 2026 Jul 15; Vol. 20 (4), pp. 562-574. <i>Date of Electronic Publication: </i>2026 Jan 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editorial+Office+of+Gut+and+Liver%22">Editorial Office of Gut and Liver </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101316452 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2005-1212 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219762283%22">19762283 </searchLink><i>NLM ISO Abbreviation: </i>Gut Liver <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 15
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