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GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast Cancer.

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Title: GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast Cancer.
Authors: Santos B; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Marção M; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA., Durdana I; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Lee B; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Vumma L; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Segato-Dezem F; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA., Chasteen H; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA., Zhang S; O'Donnell SPH-Health Data Sci Biostats, Dallas, TX, USA., Lewis C; O'Donnell SPH-Health Data Sci Biostats, Dallas, TX, USA., Peng Y; Pathology Department & Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., LeVee A; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Wong M; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Mortimer J; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., McArthur H; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Scherer PE; Touchstone Diabetes Center, UT Southwestern Medical Center, Dallas, TX., Plummer JT; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA., Gruber J; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
Source: Research square [Res Sq] 2026 Jan 09. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Santos+B%22">Santos B</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Marção+M%22">Marção M</searchLink>; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Durdana+I%22">Durdana I</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lee+B%22">Lee B</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Vumma+L%22">Vumma L</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Segato-Dezem+F%22">Segato-Dezem F</searchLink>; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Chasteen+H%22">Chasteen H</searchLink>; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; O'Donnell SPH-Health Data Sci Biostats, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+C%22">Lewis C</searchLink>; O'Donnell SPH-Health Data Sci Biostats, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Pathology Department & Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22LeVee+A%22">LeVee A</searchLink>; City of Hope Comprehensive Cancer Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wong+M%22">Wong M</searchLink>; City of Hope Comprehensive Cancer Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mortimer+J%22">Mortimer J</searchLink>; City of Hope Comprehensive Cancer Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22McArthur+H%22">McArthur H</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Scherer+PE%22">Scherer PE</searchLink>; Touchstone Diabetes Center, UT Southwestern Medical Center, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Plummer+JT%22">Plummer JT</searchLink>; Center for Spatial Omics, St Jude Children's Research Hospital, Tennessee, USA.; Department of Developmental Biology, St Jude Children's Research Hospital, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Gruber+J%22">Gruber J</searchLink>; Internal Medicine, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
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        Text: English
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