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mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope.

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Title: mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope.
Authors: Paul HT; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA., Mimms JL; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA., Aboueid H; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA., Buitrago LS; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA., Kulakova L; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA., Wilcox X; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA., Kuhn K; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA., Zhang H; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Toth EA; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA., Skinner N; The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.; Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA., Flyak AI; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA., Ofek G; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA., Benjamin Larman H; Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Fuerst TR; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA., Ray SC; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Cox AL; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bailey JR; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 07. Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope.
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  Data: <searchLink fieldCode="AU" term="%22Paul+HT%22">Paul HT</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.<br /><searchLink fieldCode="AU" term="%22Mimms+JL%22">Mimms JL</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.<br /><searchLink fieldCode="AU" term="%22Aboueid+H%22">Aboueid H</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.<br /><searchLink fieldCode="AU" term="%22Buitrago+LS%22">Buitrago LS</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.<br /><searchLink fieldCode="AU" term="%22Kulakova+L%22">Kulakova L</searchLink>; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wilcox+X%22">Wilcox X</searchLink>; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kuhn+K%22">Kuhn K</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Toth+EA%22">Toth EA</searchLink>; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Skinner+N%22">Skinner N</searchLink>; The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.; Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Flyak+AI%22">Flyak AI</searchLink>; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ofek+G%22">Ofek G</searchLink>; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA.<br /><searchLink fieldCode="AU" term="%22Benjamin+Larman+H%22">Benjamin Larman H</searchLink>; Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fuerst+TR%22">Fuerst TR</searchLink>; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA.<br /><searchLink fieldCode="AU" term="%22Ray+SC%22">Ray SC</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cox+AL%22">Cox AL</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bailey+JR%22">Bailey JR</searchLink>; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
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