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A Closed Computational-Experimental Loop Identifies Metabolic Collapse at the Root of Macrophage Dysfunction due to Zinc Dyshomeostasis.

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Title: A Closed Computational-Experimental Loop Identifies Metabolic Collapse at the Root of Macrophage Dysfunction due to Zinc Dyshomeostasis.
Authors: Malla S; Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, NE., Smith DR; Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE., Peer AM; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE., Samuelson DR; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE., Knoell DL; Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE., Saha R; Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, NE.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 11. Date of Electronic Publication: 2026 Jan 11.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 41542542
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PubType: Academic Journal
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  Data: <searchLink fieldCode="AU" term="%22Malla+S%22">Malla S</searchLink>; Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, NE.<br /><searchLink fieldCode="AU" term="%22Smith+DR%22">Smith DR</searchLink>; Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE.<br /><searchLink fieldCode="AU" term="%22Peer+AM%22">Peer AM</searchLink>; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE.<br /><searchLink fieldCode="AU" term="%22Samuelson+DR%22">Samuelson DR</searchLink>; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE.<br /><searchLink fieldCode="AU" term="%22Knoell+DL%22">Knoell DL</searchLink>; Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.; Pulmonary Division, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE.<br /><searchLink fieldCode="AU" term="%22Saha+R%22">Saha R</searchLink>; Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, NE.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Jan 11. <i>Date of Electronic Publication: </i>2026 Jan 11.
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        Value: 10.64898/2026.01.09.698698
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        Text: English
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