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The splice of life: how alternative splicing shapes regulatory and phenotypic evolution.

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Title: The splice of life: how alternative splicing shapes regulatory and phenotypic evolution.
Authors: Hunter CE; Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Veterinary Medical Scientist Training Program, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19104, USA., Xing Y; Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. xingyi@chop.edu.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. xingyi@chop.edu.; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. xingyi@chop.edu.
Source: The EMBO journal [EMBO J] 2026 Mar; Vol. 45 (6), pp. 1878-1888. Date of Electronic Publication: 2026 Jan 16.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hunter+CE%22">Hunter CE</searchLink>; Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Veterinary Medical Scientist Training Program, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Xing+Y%22">Xing Y</searchLink>; Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. xingyi@chop.edu.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. xingyi@chop.edu.; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. xingyi@chop.edu.
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      – TitleFull: The splice of life: how alternative splicing shapes regulatory and phenotypic evolution.
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              Text: 2026 Mar
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