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Low tumoral Trefoil Factor 1 expression relates to aggressive tumor features and poor survival in young women with breast cancer.

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Title: Low tumoral Trefoil Factor 1 expression relates to aggressive tumor features and poor survival in young women with breast cancer.
Authors: Kvamme AB; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway., Hugaas U; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway., Sæle AKM; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway., Ingebriktsen LM; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Medical Biochemistry and Microbiology (IMBIM), Uppsala University, Uppsala, Sweden., Svanøe AA; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway., Humlevik ROC; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway., Winge I; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway., Aas T; Department of Surgery, Haukeland University Hospital, Bergen, Norway., Heie A; Department of Surgery, Haukeland University Hospital, Bergen, Norway., Akslen LA; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden., Hoivik EA; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway., Wik E; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway. Elisabeth.Wik@uib.no.; Department of Pathology, Haukeland University Hospital, Bergen, Norway. Elisabeth.Wik@uib.no.
Source: Scientific reports [Sci Rep] 2026 Jan 17; Vol. 16 (1), pp. 5612. Date of Electronic Publication: 2026 Jan 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kvamme+AB%22">Kvamme AB</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Hugaas+U%22">Hugaas U</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Sæle+AKM%22">Sæle AKM</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Ingebriktsen+LM%22">Ingebriktsen LM</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Medical Biochemistry and Microbiology (IMBIM), Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Svanøe+AA%22">Svanøe AA</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Humlevik+ROC%22">Humlevik ROC</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Winge+I%22">Winge I</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Aas+T%22">Aas T</searchLink>; Department of Surgery, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Heie+A%22">Heie A</searchLink>; Department of Surgery, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Akslen+LA%22">Akslen LA</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hoivik+EA%22">Hoivik EA</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Wik+E%22">Wik E</searchLink>; Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, N-5021, Bergen, Norway. Elisabeth.Wik@uib.no.; Department of Pathology, Haukeland University Hospital, Bergen, Norway. Elisabeth.Wik@uib.no.
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