MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats.
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| Title: | MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats. |
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| Authors: | Kravtsova O; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Tan Y; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark., Levchenko V; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Kovalenko E; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark., Tiwari R; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Zietara A; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Bohovyk R; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Dissanayake LV; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Van TT; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA., Sharp TE 3rd; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.; Hypertension and Kidney Research Center, University of South Florida, Tampa, FL 33602, USA., Geurts AM; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Palygin O; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA., Rinschen MM; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.; Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Staruschenko A; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.; Hypertension and Kidney Research Center, University of South Florida, Tampa, FL 33602, USA.; James A. Haley Veteran's Hospital, Tampa, FL 33612, USA. |
| Source: | IScience [iScience] 2025 Dec 19; Vol. 29 (1), pp. 114505. Date of Electronic Publication: 2025 Dec 19 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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