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Early-life cognitive intervention preserves brain function in aged TgF344-AD rats with sex-specific effects.

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Title: Early-life cognitive intervention preserves brain function in aged TgF344-AD rats with sex-specific effects.
Authors: Casanova-Pagola J; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., Varriano F; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., López-Gil X; IDIBAPS, Magnetic Resonance Imaging Core Facility, Carrer del Rosselló 149-153, 08036 Barcelona, Spain., Campoy-Campos G; Biomedicine Department, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., Abellí-Deulofeu E; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., García-González C; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., López-Bravo E; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain., Tudela R; CIBER de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Avenida Monforte de Lemos 3-5, 28029 Madrid, Spain., Muñoz-Moreno E; IDIBAPS, Magnetic Resonance Imaging Core Facility, Carrer del Rosselló 149-153, 08036 Barcelona, Spain., Aguado F; Department of Cell Biology, Physiology and Immunology, Biology Faculty, University of Barcelona, Carrer Diagonal 643, 08028 Barcelona, Spain., Prats-Galino A; Laboratory of Surgical Neuroanatomy (LSNA), Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain., Molina-Porcel L; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, I Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) and University of Barcelona, Carrer del Rosselló 149-153, 08036 Barcelona, Spain.; Neurological Tissue Bank, Biobanc-Hospital Clínic-FRCB-IDIBAPS, Carrer del Rosselló 149-153, 08036 Barcelona, Spain., Malagelada C; Biomedicine Department, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Avenida Monforte de Lemos 3-5, 28029 Madrid, Spain., Soria G; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.
Source: IScience [iScience] 2025 Dec 09; Vol. 29 (1), pp. 114381. Date of Electronic Publication: 2025 Dec 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Early-life cognitive intervention preserves brain function in aged TgF344-AD rats with sex-specific effects.
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  Data: <searchLink fieldCode="AU" term="%22Casanova-Pagola+J%22">Casanova-Pagola J</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Varriano+F%22">Varriano F</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López-Gil+X%22">López-Gil X</searchLink>; IDIBAPS, Magnetic Resonance Imaging Core Facility, Carrer del Rosselló 149-153, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Campoy-Campos+G%22">Campoy-Campos G</searchLink>; Biomedicine Department, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Abellí-Deulofeu+E%22">Abellí-Deulofeu E</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-González+C%22">García-González C</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López-Bravo+E%22">López-Bravo E</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tudela+R%22">Tudela R</searchLink>; CIBER de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Avenida Monforte de Lemos 3-5, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Moreno+E%22">Muñoz-Moreno E</searchLink>; IDIBAPS, Magnetic Resonance Imaging Core Facility, Carrer del Rosselló 149-153, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Aguado+F%22">Aguado F</searchLink>; Department of Cell Biology, Physiology and Immunology, Biology Faculty, University of Barcelona, Carrer Diagonal 643, 08028 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Prats-Galino+A%22">Prats-Galino A</searchLink>; Laboratory of Surgical Neuroanatomy (LSNA), Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Molina-Porcel+L%22">Molina-Porcel L</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, I Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) and University of Barcelona, Carrer del Rosselló 149-153, 08036 Barcelona, Spain.; Neurological Tissue Bank, Biobanc-Hospital Clínic-FRCB-IDIBAPS, Carrer del Rosselló 149-153, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Malagelada+C%22">Malagelada C</searchLink>; Biomedicine Department, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Avenida Monforte de Lemos 3-5, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Soria+G%22">Soria G</searchLink>; Brain Connectivity and Neuroimaging Lab, Institute of Neurosciences, Faculty of Medicine and Health Sciences, University of Barcelona, Carrer de Casanova 143, 08036 Barcelona, Spain.
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