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Type I error control and interim monitoring for co-primary hypotheses involving a subgroup in the Outpatient Treatment with Anti-Coronavirus Immunoglobulin (OTAC) trial.

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Title: Type I error control and interim monitoring for co-primary hypotheses involving a subgroup in the Outpatient Treatment with Anti-Coronavirus Immunoglobulin (OTAC) trial.
Authors: Hu J; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA., Babiker AG; Medical Research Council Clinical Trials Unit at UCL, University College London, London, UK., Reilly CS; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA., Baker JV; Division of Infectious Diseases and International Medicine, University of Minnesota, MN, USA.; Division of Infectious Diseases, Hennepin Healthcare, MN, USA., Siegel LK; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA.
Source: Contemporary clinical trials communications [Contemp Clin Trials Commun] 2025 Dec 24; Vol. 49, pp. 101592. Date of Electronic Publication: 2025 Dec 24 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101671157 Publication Model: eCollection Cited Medium: Internet ISSN: 2451-8654 (Electronic) Linking ISSN: 24518654 NLM ISO Abbreviation: Contemp Clin Trials Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hu+J%22">Hu J</searchLink>; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA.<br /><searchLink fieldCode="AU" term="%22Babiker+AG%22">Babiker AG</searchLink>; Medical Research Council Clinical Trials Unit at UCL, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Reilly+CS%22">Reilly CS</searchLink>; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA.<br /><searchLink fieldCode="AU" term="%22Baker+JV%22">Baker JV</searchLink>; Division of Infectious Diseases and International Medicine, University of Minnesota, MN, USA.; Division of Infectious Diseases, Hennepin Healthcare, MN, USA.<br /><searchLink fieldCode="AU" term="%22Siegel+LK%22">Siegel LK</searchLink>; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, MN, USA.
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  Data: <searchLink fieldCode="JN" term="%22101671157%22">Contemporary clinical trials communications</searchLink> [Contemp Clin Trials Commun] 2025 Dec 24; Vol. 49, pp. 101592. <i>Date of Electronic Publication: </i>2025 Dec 24 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101671157 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2451-8654 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224518654%22">24518654 </searchLink><i>NLM ISO Abbreviation: </i>Contemp Clin Trials Commun <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: Type I error control and interim monitoring for co-primary hypotheses involving a subgroup in the Outpatient Treatment with Anti-Coronavirus Immunoglobulin (OTAC) trial.
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              Text: 2025 Dec 24
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