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Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes.

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Title: Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes.
Authors: Hollek V; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany., Böhning F; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Florez Vargas C; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany., Sieber A; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany., Morkel M; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Blüthgen N; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany. nils.bluethgen@charite.de.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany. nils.bluethgen@charite.de.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. nils.bluethgen@charite.de.; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin, 10117, Germany. nils.bluethgen@charite.de.
Source: Molecular systems biology [Mol Syst Biol] 2026 Mar; Vol. 22 (3), pp. 435-460. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hollek+V%22">Hollek V</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany.<br /><searchLink fieldCode="AU" term="%22Böhning+F%22">Böhning F</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.<br /><searchLink fieldCode="AU" term="%22Florez+Vargas+C%22">Florez Vargas C</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.<br /><searchLink fieldCode="AU" term="%22Sieber+A%22">Sieber A</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.<br /><searchLink fieldCode="AU" term="%22Morkel+M%22">Morkel M</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.<br /><searchLink fieldCode="AU" term="%22Blüthgen+N%22">Blüthgen N</searchLink>; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, Berlin, 10117, Germany. nils.bluethgen@charite.de.; Institute of Biology, Humboldt Universität zu Berlin, Philippstr. 13, Berlin, 10115, Germany. nils.bluethgen@charite.de.; German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. nils.bluethgen@charite.de.; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin, 10117, Germany. nils.bluethgen@charite.de.
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  Data: <searchLink fieldCode="JN" term="%22101235389%22">Molecular systems biology</searchLink> [Mol Syst Biol] 2026 Mar; Vol. 22 (3), pp. 435-460. <i>Date of Electronic Publication: </i>2026 Jan 19.
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              Text: 2026 Mar
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