Inhibition of FOS-Like Antigen 1 Reduces Chemoresistance to Temozolomide Through Stemness Reprogramming via IL-6/STAT3Tyr705 Pathway.

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Title: Inhibition of FOS-Like Antigen 1 Reduces Chemoresistance to Temozolomide Through Stemness Reprogramming via IL-6/STAT3Tyr705 Pathway.
Authors: Sim J; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea., Park J; Department of Medicine, College of Medicine Hallym University Chuncheon Republic of Korea., Heo J; Department of Pathology, Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea., Kim YJ; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea., Kim D; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea., Jeon YH; Preclinical Research Center (PRC) Daegu-Gyeonbuk Medical Innovation Foundation (K-Medi Hub) Daegu Republic of Korea., Lee JE; Preclinical Research Center (PRC) Daegu-Gyeonbuk Medical Innovation Foundation (K-Medi Hub) Daegu Republic of Korea., Choi SH; Department of Radiology Pusan National University Hospital Biomedical Institute of Pusan National University Hospital Pusan National University School of Medicine Busan Republic of Korea., Kim HJ; Department of Radiology Pusan National University Hospital Biomedical Institute of Pusan National University Hospital Pusan National University School of Medicine Busan Republic of Korea., Hwang SJ; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.; Development Division CG Cell Corporation Seongnam Republic of Korea., Kim J; Department of Integrated Biomedical Science Soonchunhyang Institute of Medi-bio Science (SIMS) Soonchunhyang University Cheonan Republic of Korea.; Department of Biology Education Kongju National University Gongju Republic of Korea., Cho KG; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea., Yoo J; Department of Neurosurgery Brain Tumor Center Gangnam Severance Hospital Seoul Republic of Korea., Moon JH; Department of Neurosurgery Endoscopic Skull Base Center Severance Hospital Yonsei University College of Medicine Seoul Republic of Korea., Moon JS; Department of Integrated Biomedical Science Soonchunhyang Institute of Medi-bio Science (SIMS) Soonchunhyang University Cheonan Republic of Korea.; Department of Pathology College of Medicine Soonchunhyang University Cheonan Republic of Korea., Sung KS; Department of Neurosurgery Dong-A University Hospital, Dong-A University College of Medicine Busan Republic of Korea., Lim J; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea.; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.
Source: MedComm [MedComm (2020)] 2026 Jan 18; Vol. 7 (2), pp. e70593. Date of Electronic Publication: 2026 Jan 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: China NLM ID: 101769925 Publication Model: eCollection Cited Medium: Internet ISSN: 2688-2663 (Electronic) Linking ISSN: 26882663 NLM ISO Abbreviation: MedComm (2020) Subsets: PubMed not MEDLINE
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  Data: Inhibition of FOS-Like Antigen 1 Reduces Chemoresistance to Temozolomide Through Stemness Reprogramming via IL-6/STAT3<superscript>Tyr705</superscript> Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Sim+J%22">Sim J</searchLink>; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Medicine, College of Medicine Hallym University Chuncheon Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+J%22">Heo J</searchLink>; Department of Pathology, Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YJ%22">Kim YJ</searchLink>; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+YH%22">Jeon YH</searchLink>; Preclinical Research Center (PRC) Daegu-Gyeonbuk Medical Innovation Foundation (K-Medi Hub) Daegu Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Preclinical Research Center (PRC) Daegu-Gyeonbuk Medical Innovation Foundation (K-Medi Hub) Daegu Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SH%22">Choi SH</searchLink>; Department of Radiology Pusan National University Hospital Biomedical Institute of Pusan National University Hospital Pusan National University School of Medicine Busan Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Radiology Pusan National University Hospital Biomedical Institute of Pusan National University Hospital Pusan National University School of Medicine Busan Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+SJ%22">Hwang SJ</searchLink>; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.; Development Division CG Cell Corporation Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Integrated Biomedical Science Soonchunhyang Institute of Medi-bio Science (SIMS) Soonchunhyang University Cheonan Republic of Korea.; Department of Biology Education Kongju National University Gongju Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+KG%22">Cho KG</searchLink>; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+J%22">Yoo J</searchLink>; Department of Neurosurgery Brain Tumor Center Gangnam Severance Hospital Seoul Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JH%22">Moon JH</searchLink>; Department of Neurosurgery Endoscopic Skull Base Center Severance Hospital Yonsei University College of Medicine Seoul Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JS%22">Moon JS</searchLink>; Department of Integrated Biomedical Science Soonchunhyang Institute of Medi-bio Science (SIMS) Soonchunhyang University Cheonan Republic of Korea.; Department of Pathology College of Medicine Soonchunhyang University Cheonan Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sung+KS%22">Sung KS</searchLink>; Department of Neurosurgery Dong-A University Hospital, Dong-A University College of Medicine Busan Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+J%22">Lim J</searchLink>; Department of Biomedical Science, College of Life Science CHA University Seongnam Republic of Korea.; CHA Future Medicine Research Institute CHA Bundang Medical Center Seongnam Republic of Korea.; Department of Neurosurgery Bundang CHA Medical Center CHA University College of Medicine Seongnam Republic of Korea.
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