KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment.
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| Title: | KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment. |
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| Authors: | Burge RA; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Le Roux O; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina., Popow O; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham & Women's Hospital, and Harvard Medical School, Boston, Massachusetts., Spadafora VK; Department of Pediatrics, Darby Children's Research Institute, Medical University of South Carolina, Charleston, South Carolina., Rajesh C; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Adair SJ; Department of Surgery, University of Virginia, Charlottesville, Virginia., Bialousow L; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Murphy C; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Saberi S; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Vaena SG; Bioinformatics Core, Medical University of South Carolina, Charleston, South Carolina., Taquey MC; College of Graduate Studies, Medical University of South Carolina, Charleston, South Carolina., Allen S; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Han L; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina., Helke KL; Department of Comparative Medicine, Medical University of South Carolina, Charleston, South Carolina., Sharma S; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Ostrowski MC; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina., Guttridge DC; Department of Pediatrics, Darby Children's Research Institute, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina., Dincman TA; Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina.; Division of Hematology and Oncology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina., Bauer TW; Department of Surgery, University of Virginia, Charlottesville, Virginia., Kashatus DF; Department Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia., McFall T; Department of Biochemistry and MCW Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin., Haigis KM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham & Women's Hospital, and Harvard Medical School, Boston, Massachusetts., Hollingsworth MA; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska., Counter CM; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina., Der CJ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Hobbs GA; Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina. |
| Source: | Cancer research [Cancer Res] 2026 Apr 15; Vol. 86 (8), pp. 1868-1882. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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