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Real-world effectiveness of biologic therapies in severe asthma patients ineligible for phase 3 randomised controlled trials of biologics: an analysis from the UK Severe Asthma Registry.

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Title: Real-world effectiveness of biologic therapies in severe asthma patients ineligible for phase 3 randomised controlled trials of biologics: an analysis from the UK Severe Asthma Registry.
Authors: Pfeffer PE; Barts Health NHS Trust, London, UK.; Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karaj J; Barts Health NHS Trust, London, UK., Brown T; Portsmouth Hospitals University NHS Trust, Portsmouth, UK., Burhan H; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Chaudhuri R; Gartnavel General Hospital and University of Glasgow, Glasgow, UK., Prior K; Lancashire Teaching Hospitals NHS Foundation Trust, Lancashire, UK., Siddiqui S; National Heart and Lung Institute, Imperial College, London, UK., Heaney L; Queen's University, Belfast, UK., Jackson DJ; School of Immunology and Microbial Sciences, King's College London, London, UK.; Guy's and St Thomas' NHS Trust, London, UK., Patel M; Derriford Hospital, Plymouth, UK., Patel PH; Royal Brompton Hospital, London, UK.; Imperial College, London, UK., Rupani H; University Southampton NHS Foundation Trust, Southampton, UK., Busby J; Centre for Public Health, Queen's University, Belfast, UK.
Source: ERJ open research [ERJ Open Res] 2026 Jan 19; Vol. 12 (1). Date of Electronic Publication: 2026 Jan 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world effectiveness of biologic therapies in severe asthma patients ineligible for phase 3 randomised controlled trials of biologics: an analysis from the UK Severe Asthma Registry.
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  Data: <searchLink fieldCode="AU" term="%22Pfeffer+PE%22">Pfeffer PE</searchLink>; Barts Health NHS Trust, London, UK.; Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Karaj+J%22">Karaj J</searchLink>; Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Brown+T%22">Brown T</searchLink>; Portsmouth Hospitals University NHS Trust, Portsmouth, UK.<br /><searchLink fieldCode="AU" term="%22Burhan+H%22">Burhan H</searchLink>; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+R%22">Chaudhuri R</searchLink>; Gartnavel General Hospital and University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Prior+K%22">Prior K</searchLink>; Lancashire Teaching Hospitals NHS Foundation Trust, Lancashire, UK.<br /><searchLink fieldCode="AU" term="%22Siddiqui+S%22">Siddiqui S</searchLink>; National Heart and Lung Institute, Imperial College, London, UK.<br /><searchLink fieldCode="AU" term="%22Heaney+L%22">Heaney L</searchLink>; Queen's University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Jackson+DJ%22">Jackson DJ</searchLink>; School of Immunology and Microbial Sciences, King's College London, London, UK.; Guy's and St Thomas' NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Patel+M%22">Patel M</searchLink>; Derriford Hospital, Plymouth, UK.<br /><searchLink fieldCode="AU" term="%22Patel+PH%22">Patel PH</searchLink>; Royal Brompton Hospital, London, UK.; Imperial College, London, UK.<br /><searchLink fieldCode="AU" term="%22Rupani+H%22">Rupani H</searchLink>; University Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Busby+J%22">Busby J</searchLink>; Centre for Public Health, Queen's University, Belfast, UK.
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  Data: <searchLink fieldCode="JN" term="%22101671641%22">ERJ open research</searchLink> [ERJ Open Res] 2026 Jan 19; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Jan 19 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22European+Respiratory+Society%22">European Respiratory Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101671641 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2312-0541 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223120541%22">23120541 </searchLink><i>NLM ISO Abbreviation: </i>ERJ Open Res <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1183/23120541.00565-2025
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        Text: English
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              Text: 2026 Jan 19
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