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Mesangial Cell-Derived Extracellular Matrix Protein 1 Is Essential for Maintaining Mesangial Matrix Homeostasis and Glomerular Architecture.

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Title: Mesangial Cell-Derived Extracellular Matrix Protein 1 Is Essential for Maintaining Mesangial Matrix Homeostasis and Glomerular Architecture.
Authors: Deng P; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhou H; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Yu J; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Li Y; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Yang F; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhang D; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China., Zhou M; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Luo J; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Gao L; Department of Neurobiology, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China., Bi E; Department of Biochemistry and Molecular Biology, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China., Guo N; Department of Neurobiology, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China., Nie J; State Key Laboratory of Vascular Homeostasis and Remodeling, Biobank of Peking University First Hospital, Peking University Health Science Center, Peking University First Hospital, Peking University, Beijing, China., Sun B; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China., Hou FF; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Hu Y; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Jun 01; Vol. 37 (6), pp. 1206-1220. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mesangial Cell-Derived Extracellular Matrix Protein 1 Is Essential for Maintaining Mesangial Matrix Homeostasis and Glomerular Architecture.
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  Data: <searchLink fieldCode="AU" term="%22Deng+P%22">Deng P</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+F%22">Yang F</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+M%22">Zhou M</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Luo+J%22">Luo J</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Department of Neurobiology, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Bi+E%22">Bi E</searchLink>; Department of Biochemistry and Molecular Biology, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+N%22">Guo N</searchLink>; Department of Neurobiology, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Nie+J%22">Nie J</searchLink>; State Key Laboratory of Vascular Homeostasis and Remodeling, Biobank of Peking University First Hospital, Peking University Health Science Center, Peking University First Hospital, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+B%22">Sun B</searchLink>; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hou+FF%22">Hou FF</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Division of Nephrology, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Provincial Key Laboratory of Renal Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%229013836%22">Journal of the American Society of Nephrology : JASN</searchLink> [J Am Soc Nephrol] 2026 Jun 01; Vol. 37 (6), pp. 1206-1220. <i>Date of Electronic Publication: </i>2025 Dec 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+on+behalf+of+the+American+Society+of+Nephrology%22">Wolters Kluwer Health, on behalf of the American Society of Nephrology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9013836 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-3450 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210466673%22">10466673 </searchLink><i>NLM ISO Abbreviation: </i>J Am Soc Nephrol <i>Subsets: </i>MEDLINE
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        Value: 10.1681/ASN.0000000969
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              Text: 2026 Jun 01
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