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A case of synchronous multiple primary lung cancers each harboring an EGFR mutation or an ALK fusion gene alone that responded to osimertinib with chemotherapy.

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Title: A case of synchronous multiple primary lung cancers each harboring an EGFR mutation or an ALK fusion gene alone that responded to osimertinib with chemotherapy.
Authors: Fukui D; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Morinaga D; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Sakakibara-Konishi J; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan; Medical Network and Welfare Center, Hokkaido University Hospital, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan. Electronic address: konishj@med.hokudai.ac.jp., Yoshida Y; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Kashima M; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Ito S; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Furuta M; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Takashima Y; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Tanei Z; Department of Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan., Konno S; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
Source: Respiratory investigation [Respir Investig] 2026 Mar; Vol. 64 (2), pp. 101375. Date of Electronic Publication: 2026 Jan 20.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE
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  Data: A case of synchronous multiple primary lung cancers each harboring an EGFR mutation or an ALK fusion gene alone that responded to osimertinib with chemotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Fukui+D%22">Fukui D</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Morinaga+D%22">Morinaga D</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Sakakibara-Konishi+J%22">Sakakibara-Konishi J</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan; Medical Network and Welfare Center, Hokkaido University Hospital, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan. Electronic address: konishj@med.hokudai.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yoshida+Y%22">Yoshida Y</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Kashima+M%22">Kashima M</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+S%22">Ito S</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Furuta+M%22">Furuta M</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Takashima+Y%22">Takashima Y</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Tanei+Z%22">Tanei Z</searchLink>; Department of Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Konno+S%22">Konno S</searchLink>; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, 060-8638, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101581124%22">Respiratory investigation</searchLink> [Respir Investig] 2026 Mar; Vol. 64 (2), pp. 101375. <i>Date of Electronic Publication: </i>2026 Jan 20.
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              Text: 2026 Mar
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