View in EDS HTML Full Text PDF Full Text

CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer.

Saved in:
Bibliographic Details
Title: CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer.
Authors: Shi W; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Luo Y; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Wang Y; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Burrows JM; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia., Black D; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Civitarese A; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Perlaza-Jimenez L; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Zhang P; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Manning M; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia., Tuano N; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Rentería ME; Mental Health and Neuroscience Program, QIMR Berghofer, Brisbane, QLD, Australia., Xiao C; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Tey SK; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Rosenbluh J; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia., Smith C; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia., Chenevix-Trench G; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Beesley J; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au.
Source: NPJ breast cancer [NPJ Breast Cancer] 2026 Jan 21; Vol. 12 (1), pp. 24. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41565695
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Shi+W%22">Shi W</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Burrows+JM%22">Burrows JM</searchLink>; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Black+D%22">Black D</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Civitarese+A%22">Civitarese A</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Perlaza-Jimenez+L%22">Perlaza-Jimenez L</searchLink>; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Manning+M%22">Manning M</searchLink>; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Tuano+N%22">Tuano N</searchLink>; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Rentería+ME%22">Rentería ME</searchLink>; Mental Health and Neuroscience Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Xiao+C%22">Xiao C</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Tey+SK%22">Tey SK</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Rosenbluh+J%22">Rosenbluh J</searchLink>; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Chenevix-Trench+G%22">Chenevix-Trench G</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Beesley+J%22">Beesley J</searchLink>; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101674891%22">NPJ breast cancer</searchLink> [NPJ Breast Cancer] 2026 Jan 21; Vol. 12 (1), pp. 24. <i>Date of Electronic Publication: </i>2026 Jan 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Breast+Cancer+Research+Foundation%22">Breast Cancer Research Foundation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101674891 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2374-4677 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223744677%22">23744677 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Breast Cancer <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41565695
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41523-025-00888-8
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 24
    Titles:
      – TitleFull: CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Shi W
      – PersonEntity:
          Name:
            NameFull: Luo Y
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Burrows JM
      – PersonEntity:
          Name:
            NameFull: Black D
      – PersonEntity:
          Name:
            NameFull: Civitarese A
      – PersonEntity:
          Name:
            NameFull: Perlaza-Jimenez L
      – PersonEntity:
          Name:
            NameFull: Zhang P
      – PersonEntity:
          Name:
            NameFull: Manning M
      – PersonEntity:
          Name:
            NameFull: Tuano N
      – PersonEntity:
          Name:
            NameFull: Rentería ME
      – PersonEntity:
          Name:
            NameFull: Xiao C
      – PersonEntity:
          Name:
            NameFull: Tey SK
      – PersonEntity:
          Name:
            NameFull: Rosenbluh J
      – PersonEntity:
          Name:
            NameFull: Smith C
      – PersonEntity:
          Name:
            NameFull: Chenevix-Trench G
      – PersonEntity:
          Name:
            NameFull: Beesley J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 01
              Text: 2026 Jan 21
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2374-4677
          Numbering:
            – Type: volume
              Value: 12
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: NPJ breast cancer
              Type: main
ResultId 1