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LetA defines a structurally distinct transporter family.

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Title: LetA defines a structurally distinct transporter family.
Authors: Santarossa CC; Department of Biology, Johns Hopkins University, Baltimore, MD, USA., Li Y; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Yousef S; Department of Biology, Johns Hopkins University, Baltimore, MD, USA., Hasdemir HS; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Rodriguez CC; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Haase MAB; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Baek M; Department of Biological Sciences, Seoul National University, Seoul, Republic of Korea., Coudray N; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.; Applied Bioinformatics Laboratories, New York University School of Medicine, New York, NY, USA., Pavek JG; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA., Focke KN; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA., Silverberg AL; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.; Department of Chemistry, University of Texas at Austin, Austin, TX, USA., Bautista C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Yeh JT; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Marty MT; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.; Department of Chemistry, University of Texas at Austin, Austin, TX, USA., Baker D; Institute for Protein Design, University of Washington, Seattle, WA, USA., Tajkhorshid E; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Ekiert DC; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. damian.ekiert@be-labs.org., Bhabha G; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. gira.bhabha@be-labs.org.
Source: Nature [Nature] 2026 Mar; Vol. 651 (8107), pp. 1097-1106. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Santarossa+CC%22">Santarossa CC</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Yousef+S%22">Yousef S</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hasdemir+HS%22">Hasdemir HS</searchLink>; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+CC%22">Rodriguez CC</searchLink>; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Haase+MAB%22">Haase MAB</searchLink>; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Baek+M%22">Baek M</searchLink>; Department of Biological Sciences, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Coudray+N%22">Coudray N</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.; Applied Bioinformatics Laboratories, New York University School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pavek+JG%22">Pavek JG</searchLink>; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Focke+KN%22">Focke KN</searchLink>; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Silverberg+AL%22">Silverberg AL</searchLink>; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.; Department of Chemistry, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bautista+C%22">Bautista C</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+JT%22">Yeh JT</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Marty+MT%22">Marty MT</searchLink>; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.; Department of Chemistry, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Baker+D%22">Baker D</searchLink>; Institute for Protein Design, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tajkhorshid+E%22">Tajkhorshid E</searchLink>; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ekiert+DC%22">Ekiert DC</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. damian.ekiert@be-labs.org.<br /><searchLink fieldCode="AU" term="%22Bhabha+G%22">Bhabha G</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. gira.bhabha@be-labs.org.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Mar; Vol. 651 (8107), pp. 1097-1106. <i>Date of Electronic Publication: </i>2026 Jan 21.
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