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Preoperative positive ctDNA analysis is associated with the tumor microenvironment, and the risk of recurrence in non-metastatic colorectal cancer.

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Title: Preoperative positive ctDNA analysis is associated with the tumor microenvironment, and the risk of recurrence in non-metastatic colorectal cancer.
Authors: Gögenur M; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark. mgog@regionsjaelland.dk., Balsevicius L; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark., Jensen SØ; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Øgaard N; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Lyskjær I; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Justesen TF; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark., Bzorek M; Department of Pathology, Zealand University Hospital, Roskilde, Denmark., Fiehn AK; Department of Pathology, Zealand University Hospital, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Walker LR; Department of Surgery, Slagelse Hospital, Slagelse, Denmark., Bojesen RD; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.; Department of Surgery, Slagelse Hospital, Slagelse, Denmark., Rosen AW; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark., Andersen CL; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.; Danish Colorectal Cancer Group, Copenhagen, Denmark., Gögenur I; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Danish Colorectal Cancer Group, Copenhagen, Denmark.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Jan 21; Vol. 10 (1). Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Preoperative positive ctDNA analysis is associated with the tumor microenvironment, and the risk of recurrence in non-metastatic colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Gögenur+M%22">Gögenur M</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark. mgog@regionsjaelland.dk.<br /><searchLink fieldCode="AU" term="%22Balsevicius+L%22">Balsevicius L</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+SØ%22">Jensen SØ</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Øgaard+N%22">Øgaard N</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Lyskjær+I%22">Lyskjær I</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Justesen+TF%22">Justesen TF</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.<br /><searchLink fieldCode="AU" term="%22Bzorek+M%22">Bzorek M</searchLink>; Department of Pathology, Zealand University Hospital, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Fiehn+AK%22">Fiehn AK</searchLink>; Department of Pathology, Zealand University Hospital, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Walker+LR%22">Walker LR</searchLink>; Department of Surgery, Slagelse Hospital, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Bojesen+RD%22">Bojesen RD</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.; Department of Surgery, Slagelse Hospital, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Rosen+AW%22">Rosen AW</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.<br /><searchLink fieldCode="AU" term="%22Andersen+CL%22">Andersen CL</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.; Danish Colorectal Cancer Group, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gögenur+I%22">Gögenur I</searchLink>; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Danish Colorectal Cancer Group, Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Jan 21; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Jan 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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