Past, present and future perspectives on the science of aging.

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Title: Past, present and future perspectives on the science of aging.
Authors: Ambrosio F; Discovery Center for Musculoskeletal Recovery at the Schoen Adams Research Institute, Spaulding Rehabilitation Hospital, Charlestown, MA, USA.; Department of Physical Medicine & Rehabilitation, Harvard Medical School, Boston, MA, USA., Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Austad SN; Nathan Shock Center of Excellence in the Basic Biology of Aging, University of Alabama at Birmingham, Birmingham, AL, USA.; Integrative Center for Aging Research, University of Alabama at Birmingham, Birmingham, AL, USA., Barzilai N; The Academy of Health & Lifespan Research, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA., Belmonte JCI; Altos Labs, San Diego Institute of Science, San Diego, CA, USA., Belsky DW; Robert N Butler Columbia Aging Center, Columbia University Mailman School of Public Health New York, New York, NY, USA., Benayoun BA; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Brunet A; Stanford University, Stanford, CA, USA., Dönertaş HM; The Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany., Dubal DB; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, USA., Fang EF; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway.; The Norwegian Centre on Healthy Ageing (NO-Age) Network, Oslo, Norway.; Norwegian National Anti-Alzheimer's Disease (NO-AD) Network, Oslo, Norway., Feige JN; Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.; EPFL School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Fried LP; Butler Columbia Aging Center, Columbia University, New York, NY, USA., Furman D; Buck Institute for Research on Aging, Novato, CA, USA., Gao X; School of Public Health, Peking University, Beijing, China., Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Gorbunova V; Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester, Rochester, NY, USA., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA., Han JJ; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden., Hara E; Department of Molecular Biology, Research Institute for Microbial Diseases, Aging Biology, Immunology Frontier Research Center, The University of Osaka, Osaka, Japan., Horvath S; David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Altos Labs, Cambridge, UK., Ip NY; Division of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong Special Administrative Region, China.; InnoHK Hong Kong Center for Neurodegenerative Diseases, Hong Kong, Hong Kong Special Administrative Region, China., Kuchel GA; UConn Center on Aging, University of Connecticut Health Center, Farmington, CT, USA., Kaeberlein M; Optispan, Inc., Seattle, WA, USA., Lamming DW; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA., Levy BR; Department of Social and Behavioral Science, Yale School of Public Health, New Haven, CT, USA., Liu GH; Chinese Academy of Sciences, Beijing, China., Lee J; University of Southern California, Los Angeles, CA, USA., Moffitt TE; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Minamino T; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan., Partridge L; Institute of Healthy Ageing and GEE, University College London, London, UK., Raina P; McMaster Institute for Research on Aging (MIRA), McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Rando TA; Broad Stem Cell Research Center, Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA., Rowe JW; Columbia Aging Center, Columbia University, New York, NY, USA., Schwartz M; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel., Scott AJ; Ellison Institute of Technology Oxford, Oxford, UK.; London Business School, London, UK., Sierra F; GeroscienceConsulting LLC, Germantown, MD, USA., Sinclair DA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Teunissen CE; Department of Laboratory Medicine, VUmc, Amsterdam, Netherlands., Vellas B; IHU HealthAge, INSERM CERPOP, CHU Toulouse University, Toulouse, France., Verdin E; Buck Institute for Research on Aging, Novato, CA, USA., Walker KA; National Institute on Aging (NIA), Intramural Research Program (IRP), National Institutes of Health, Biomedical Research Center, Baltimore, MD, USA., Webb AE; Buck Institute for Research on Aging, Novato, CA, USA., Wyss-Coray T; Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA., Xu M; Masonic Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA., Yu JT; Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China., Zhavoronkov A; Insilico Medicine, Cambridge, MA, USA., Aman Y; Nature Aging., Kriebs A; Nature Aging., Ren Q; Nature Aging., Walters H; Nature Aging., Thuault S; Nature Aging, . s.thuault@us.nature.com.
Source: Nature aging [Nat Aging] 2026 Jan; Vol. 6 (1), pp. 6-22.
Publication Type: Interview
Journal Info: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ambrosio+F%22">Ambrosio F</searchLink>; Discovery Center for Musculoskeletal Recovery at the Schoen Adams Research Institute, Spaulding Rehabilitation Hospital, Charlestown, MA, USA.; Department of Physical Medicine & Rehabilitation, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Artyomov+MN%22">Artyomov MN</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Austad+SN%22">Austad SN</searchLink>; Nathan Shock Center of Excellence in the Basic Biology of Aging, University of Alabama at Birmingham, Birmingham, AL, USA.; Integrative Center for Aging Research, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Barzilai+N%22">Barzilai N</searchLink>; The Academy of Health & Lifespan Research, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Belmonte+JCI%22">Belmonte JCI</searchLink>; Altos Labs, San Diego Institute of Science, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Belsky+DW%22">Belsky DW</searchLink>; Robert N Butler Columbia Aging Center, Columbia University Mailman School of Public Health New York, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Benayoun+BA%22">Benayoun BA</searchLink>; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brunet+A%22">Brunet A</searchLink>; Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dönertaş+HM%22">Dönertaş HM</searchLink>; The Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Dubal+DB%22">Dubal DB</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, USA.<br /><searchLink fieldCode="AU" term="%22Fang+EF%22">Fang EF</searchLink>; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway.; 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Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gorospe+M%22">Gorospe M</searchLink>; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Han+JJ%22">Han JJ</searchLink>; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Hara+E%22">Hara E</searchLink>; Department of Molecular Biology, Research Institute for Microbial Diseases, Aging Biology, Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Horvath+S%22">Horvath S</searchLink>; David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Altos Labs, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ip+NY%22">Ip NY</searchLink>; Division of Life Science, State Key Laboratory of Nervous System Disorders, Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong Special Administrative Region, China.; InnoHK Hong Kong Center for Neurodegenerative Diseases, Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Kuchel+GA%22">Kuchel GA</searchLink>; UConn Center on Aging, University of Connecticut Health Center, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Kaeberlein+M%22">Kaeberlein M</searchLink>; Optispan, Inc., Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lamming+DW%22">Lamming DW</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Levy+BR%22">Levy BR</searchLink>; Department of Social and Behavioral Science, Yale School of Public Health, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Liu+GH%22">Liu GH</searchLink>; Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Moffitt+TE%22">Moffitt TE</searchLink>; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Minamino+T%22">Minamino T</searchLink>; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Partridge+L%22">Partridge L</searchLink>; Institute of Healthy Ageing and GEE, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Raina+P%22">Raina P</searchLink>; 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Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Teunissen+CE%22">Teunissen CE</searchLink>; Department of Laboratory Medicine, VUmc, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vellas+B%22">Vellas B</searchLink>; IHU HealthAge, INSERM CERPOP, CHU Toulouse University, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Verdin+E%22">Verdin E</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Walker+KA%22">Walker KA</searchLink>; National Institute on Aging (NIA), Intramural Research Program (IRP), National Institutes of Health, Biomedical Research Center, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Webb+AE%22">Webb AE</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wyss-Coray+T%22">Wyss-Coray T</searchLink>; Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+M%22">Xu M</searchLink>; Masonic Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Yu+JT%22">Yu JT</searchLink>; Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhavoronkov+A%22">Zhavoronkov A</searchLink>; Insilico Medicine, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Aman+Y%22">Aman Y</searchLink>; Nature Aging.<br /><searchLink fieldCode="AU" term="%22Kriebs+A%22">Kriebs A</searchLink>; Nature Aging.<br /><searchLink fieldCode="AU" term="%22Ren+Q%22">Ren Q</searchLink>; Nature Aging.<br /><searchLink fieldCode="AU" term="%22Walters+H%22">Walters H</searchLink>; Nature Aging.<br /><searchLink fieldCode="AU" term="%22Thuault+S%22">Thuault S</searchLink>; Nature Aging, . s.thuault@us.nature.com.
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