Mycobacterium tuberculosis-Specific CFP-10/ESAT-6 CD4 and CD8 T-Cell Non-IFN-γ+ Responses Are Common in Young Kenyan Children Despite Low Reported Tuberculosis Exposure.

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Title: Mycobacterium tuberculosis-Specific CFP-10/ESAT-6 CD4 and CD8 T-Cell Non-IFN-γ+ Responses Are Common in Young Kenyan Children Despite Low Reported Tuberculosis Exposure.
Authors: LaCourse SM; Department of Global Health.; Division of Allergy and Infectious Diseases, Department of Medicine.; Department of Epidemiology, University of Washington, Seattle., Escudero JN; Department of Global Health., Whatney WE; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University., Krish KN; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University., Subuddhi A; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University., Belauret S; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University., Pearson RA; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University., Cranmer LM; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia., Mecha J; Centre for Respiratory Diseases Research, Kenya Medical Research Institute., Matemo D; Medical Research Department, Kenyatta National Hospital., Maleche-Obimbo E; Department of Global Health.; Department of Paediatrics and Child Health, University of Nairobi., Kinuthia J; Department of Global Health.; Medical Research Department, Kenyatta National Hospital.; Department of Reproductive Health, Kenyatta National Hospital, Nairobi, Kenya., Richardson BA; Department of Global Health.; Department of Biostatistics., John-Stewart G; Department of Global Health.; Division of Allergy and Infectious Diseases, Department of Medicine.; Department of Epidemiology, University of Washington, Seattle.; Department of Pediatrics, University of Washington, Seattle., Day CL; Department of Microbiology and Immunology, Emory University School of Medicine.; Emory Vaccine Center, Emory University.
Source: The Journal of infectious diseases [J Infect Dis] 2026 Apr 29; Vol. 233 (4), pp. e981-e989.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
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