Revealing intra-group immunotherapy response heterogeneity in metastatic urothelial carcinoma through interpretable feature extraction and spectral clustering.

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Title: Revealing intra-group immunotherapy response heterogeneity in metastatic urothelial carcinoma through interpretable feature extraction and spectral clustering.
Authors: Nagumo Y; Department of Urology, University of Tsukuba, Tsukuba, Japan., Ye X; Department of Computer Science, University of Tsukuba, Tsukuba, Japan., Shi T; Department of Computer Science, University of Tsukuba, Tsukuba, Japan., Mathis BJ; Department of Cardiovascular Surgery, University of Tsukuba Institute of Medicine, Ibaraki, Japan., Sakurai T; Department of Computer Science, University of Tsukuba, Tsukuba, Japan., Nishiyama H; Department of Urology, University of Tsukuba, Tsukuba, Japan.; Center for Cyber Medicine Research, University of Tsukuba, Ibaraki, Japan.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 06; Vol. 16, pp. 1629001. Date of Electronic Publication: 2026 Jan 06 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Nagumo+Y%22">Nagumo Y</searchLink>; Department of Urology, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Ye+X%22">Ye X</searchLink>; Department of Computer Science, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Shi+T%22">Shi T</searchLink>; Department of Computer Science, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Mathis+BJ%22">Mathis BJ</searchLink>; Department of Cardiovascular Surgery, University of Tsukuba Institute of Medicine, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Sakurai+T%22">Sakurai T</searchLink>; Department of Computer Science, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Nishiyama+H%22">Nishiyama H</searchLink>; Department of Urology, University of Tsukuba, Tsukuba, Japan.; Center for Cyber Medicine Research, University of Tsukuba, Ibaraki, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 06; Vol. 16, pp. 1629001. <i>Date of Electronic Publication: </i>2026 Jan 06 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2025.1629001
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      – TitleFull: Revealing intra-group immunotherapy response heterogeneity in metastatic urothelial carcinoma through interpretable feature extraction and spectral clustering.
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              Text: 2026 Jan 06
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