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Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities.

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Title: Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities.
Authors: Durodoye RO; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA. rod10@case.edu., Ciesielski TH; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Benchek P; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Bartlett J; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Liu S; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Naj A; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA., Kunkle B; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA., Mayeux R; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Farrer L; Department of Biostatistics, Boston University School of Public Health, Boston, USA., Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA., Pericak-Vance MA; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA., Rajabli F; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA., Tosto G; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Haines JL; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Bush WS; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA., Williams SM; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA. smw154@case.edu.
Source: Human genetics [Hum Genet] 2026 Jan 22; Vol. 145 (1), pp. 16. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE
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  Data: Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities.
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  Data: <searchLink fieldCode="AU" term="%22Durodoye+RO%22">Durodoye RO</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA. rod10@case.edu.<br /><searchLink fieldCode="AU" term="%22Ciesielski+TH%22">Ciesielski TH</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Benchek+P%22">Benchek P</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Bartlett+J%22">Bartlett J</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Naj+A%22">Naj A</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Kunkle+B%22">Kunkle B</searchLink>; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA.<br /><searchLink fieldCode="AU" term="%22Schellenberg+GD%22">Schellenberg GD</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Mayeux+R%22">Mayeux R</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, USA.<br /><searchLink fieldCode="AU" term="%22Farrer+L%22">Farrer L</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Wang+LS%22">Wang LS</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Pericak-Vance+MA%22">Pericak-Vance MA</searchLink>; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA.<br /><searchLink fieldCode="AU" term="%22Rajabli+F%22">Rajabli F</searchLink>; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA.<br /><searchLink fieldCode="AU" term="%22Tosto+G%22">Tosto G</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, USA.<br /><searchLink fieldCode="AU" term="%22Haines+JL%22">Haines JL</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Bush+WS%22">Bush WS</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22Williams+SM%22">Williams SM</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, USA. smw154@case.edu.
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  Data: <searchLink fieldCode="JN" term="%227613873%22">Human genetics</searchLink> [Hum Genet] 2026 Jan 22; Vol. 145 (1), pp. 16. <i>Date of Electronic Publication: </i>2026 Jan 22.
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