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Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations.

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Title: Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations.
Authors: Hu X; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: xiaowenh@upenn.edu., Huang J; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Yuan J; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sun Y; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wang Y; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Hu Z; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Jiang J; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wang Z; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wang B; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Long M; Division of Hematology, Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA., Maxwell KN; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA., Fan Y; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA., Tanyi JL; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA., Montone KT; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Li H; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA., Kim SH; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA., Nathanson KL; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA 19104, USA., Rebbeck TR; Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Domchek SM; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA 19104, USA., Vonderheide RH; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: rhv@upenn.edu., Zhang L; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: linzhang@upenn.edu.
Source: Cell reports [Cell Rep] 2026 Feb 24; Vol. 45 (2), pp. 116882. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations.
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  Data: <searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: xiaowenh@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+J%22">Yuan J</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+J%22">Jiang J</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Long+M%22">Long M</searchLink>; Division of Hematology, Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Maxwell+KN%22">Maxwell KN</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Tanyi+JL%22">Tanyi JL</searchLink>; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Montone+KT%22">Montone KT</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Nathanson+KL%22">Nathanson KL</searchLink>; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Rebbeck+TR%22">Rebbeck TR</searchLink>; Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Domchek+SM%22">Domchek SM</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA; Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Vonderheide+RH%22">Vonderheide RH</searchLink>; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: rhv@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Center for Women's Health and Reproductive Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: linzhang@upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 Feb 24; Vol. 45 (2), pp. 116882. <i>Date of Electronic Publication: </i>2026 Jan 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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