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Patient-derived osteosarcoma tumoroid model reveals functional phenotypic diversity with implications for drug responses.

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Title: Patient-derived osteosarcoma tumoroid model reveals functional phenotypic diversity with implications for drug responses.
Authors: Bhatia S; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia., Claxton B; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia., Thompson EW; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.; Centre for Genomics and Personalised Health, QUT, Brisbane, QLD 4059, Australia., Lowe M; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD 4102, Australia., Wagels M; Department of Plastic and Reconstructive Surgery, Princess Alexandra Hospital, Woollongabba, Brisbane, QLD 4102, Australia., Nicholls W; Oncology Services Group, Children's Health Queensland Hospital and Health Services, Queensland Children's Hospital, Brisbane, QLD 4101, Australia., Rowell P; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD 4102, Australia., Hutmacher DW; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Regenerative Medicine Group, School of Mechanical, Medical and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia.; Australian Research Council (ARC) Training Centre for Multiscale 3D imaging, Modelling, and Manufacturing (M3D Innovation), QUT, Brisbane, QLD 4000, Australia., McGovern JA; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.; ARC Training Centre for Cell and Tissue Engineering Technologies, QUT, Brisbane, QLD 4000, Australia.
Source: Biofabrication [Biofabrication] 2026 Feb 09; Vol. 18 (1). Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: IOP Pub Country of Publication: England NLM ID: 101521964 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-5090 (Electronic) Linking ISSN: 17585082 NLM ISO Abbreviation: Biofabrication Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Patient-derived osteosarcoma tumoroid model reveals functional phenotypic diversity with implications for drug responses.
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  Data: <searchLink fieldCode="AU" term="%22Bhatia+S%22">Bhatia S</searchLink>; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Claxton+B%22">Claxton B</searchLink>; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Thompson+EW%22">Thompson EW</searchLink>; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.; Centre for Genomics and Personalised Health, QUT, Brisbane, QLD 4059, Australia.<br /><searchLink fieldCode="AU" term="%22Lowe+M%22">Lowe M</searchLink>; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Wagels+M%22">Wagels M</searchLink>; Department of Plastic and Reconstructive Surgery, Princess Alexandra Hospital, Woollongabba, Brisbane, QLD 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Nicholls+W%22">Nicholls W</searchLink>; Oncology Services Group, Children's Health Queensland Hospital and Health Services, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.<br /><searchLink fieldCode="AU" term="%22Rowell+P%22">Rowell P</searchLink>; Orthopaedics Department, Princess Alexandra Hospital, Metro South Hospital and Health Services, Brisbane, QLD 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Hutmacher+DW%22">Hutmacher DW</searchLink>; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Regenerative Medicine Group, School of Mechanical, Medical and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia.; Australian Research Council (ARC) Training Centre for Multiscale 3D imaging, Modelling, and Manufacturing (M3D Innovation), QUT, Brisbane, QLD 4000, Australia.<br /><searchLink fieldCode="AU" term="%22McGovern+JA%22">McGovern JA</searchLink>; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4102, Australia.; Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, QUT, Brisbane, QLD 4059, Australia.; Centre for Biomedical Technologies, QUT, Brisbane, QLD 4059, Australia.; Translational Research Institute (TRI), Brisbane, QLD 4102, Australia.; ARC Training Centre for Cell and Tissue Engineering Technologies, QUT, Brisbane, QLD 4000, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101521964%22">Biofabrication</searchLink> [Biofabrication] 2026 Feb 09; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Feb 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22IOP+Pub%22">IOP Pub </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101521964 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-5090 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217585082%22">17585082 </searchLink><i>NLM ISO Abbreviation: </i>Biofabrication <i>Subsets: </i>MEDLINE
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        Value: 10.1088/1758-5090/ae3c44
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              Text: 2026 Feb 09
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