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The cGAS-STING pathway in fibroblast microenvironment: from molecular mechanisms to targeted therapies.

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Title: The cGAS-STING pathway in fibroblast microenvironment: from molecular mechanisms to targeted therapies.
Authors: Zhang Z; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Deng H; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Zhang X; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Li J; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Zhao J; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Liu J; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Deng C; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China., Yang Y; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China. yang200214yy@nwu.edu.cn., Liang Z; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East, Zhengzhou, 450052, China. fccliangzx@zzu.edu.cn.
Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2026 Jan 23; Vol. 31 (2), pp. 53. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-675X (Electronic) Linking ISSN: 13608185 NLM ISO Abbreviation: Apoptosis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: The cGAS-STING pathway in fibroblast microenvironment: from molecular mechanisms to targeted therapies.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Deng+H%22">Deng H</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.<br /><searchLink fieldCode="AU" term="%22Deng+C%22">Deng C</searchLink>; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China. yang200214yy@nwu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liang+Z%22">Liang Z</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East, Zhengzhou, 450052, China. fccliangzx@zzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229712129%22">Apoptosis : an international journal on programmed cell death</searchLink> [Apoptosis] 2026 Jan 23; Vol. 31 (2), pp. 53. <i>Date of Electronic Publication: </i>2026 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9712129 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-675X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213608185%22">13608185 </searchLink><i>NLM ISO Abbreviation: </i>Apoptosis <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10495-026-02268-4
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      – Code: eng
        Text: English
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        StartPage: 53
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              Text: 2026 Jan 23
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              Y: 2026
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