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A dual role of hippocampal perineuronal nets in plasticity and protection is revealed by improvement and impairment of diet-induced memory dysfunction.

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Title: A dual role of hippocampal perineuronal nets in plasticity and protection is revealed by improvement and impairment of diet-induced memory dysfunction.
Authors: Reichelt AC; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia., Hashad AM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Ghosh-Swaby OR; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada. oghoshsw@uwo.ca.; Western Institute for Neuroscience, Western University, London, ON, Canada. oghoshsw@uwo.ca., Skirzewski M; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada., Scott GA; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada., Machado M; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada., Kramar CP; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, QC, Canada., Princz-Lebel O; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada., Inoue W; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Bussey TJ; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada., Saksida LM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 Jun; Vol. 51 (7), pp. 1245-1257. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Reichelt+AC%22">Reichelt AC</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Hashad+AM%22">Hashad AM</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Ghosh-Swaby+OR%22">Ghosh-Swaby OR</searchLink>; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada. oghoshsw@uwo.ca.; Western Institute for Neuroscience, Western University, London, ON, Canada. oghoshsw@uwo.ca.<br /><searchLink fieldCode="AU" term="%22Skirzewski+M%22">Skirzewski M</searchLink>; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Scott+GA%22">Scott GA</searchLink>; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.<br /><searchLink fieldCode="AU" term="%22Machado+M%22">Machado M</searchLink>; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.<br /><searchLink fieldCode="AU" term="%22Kramar+CP%22">Kramar CP</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Princz-Lebel+O%22">Princz-Lebel O</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.<br /><searchLink fieldCode="AU" term="%22Inoue+W%22">Inoue W</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bussey+TJ%22">Bussey TJ</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Saksida+LM%22">Saksida LM</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, On, Canada.; Western Institute for Neuroscience, Western University, London, ON, Canada.
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