A dual role of hippocampal perineuronal nets in plasticity and protection is revealed by improvement and impairment of diet-induced memory dysfunction. - Reichelt AC; Hashad AM; Ghosh-Swaby OR; Skirzewski M; Scott GA; Machado M; Kramar CP; Princz-Lebel O; Inoue W; Bussey TJ; Saksida LM (Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026)