Authors reply: "Associations of positive end-expiratory pressure (PEEP) with extubation failure and clinical outcomes in invasively ventilated patients with acute brain injury: A secondary analysis of the ENIO study".

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Title: Authors reply: "Associations of positive end-expiratory pressure (PEEP) with extubation failure and clinical outcomes in invasively ventilated patients with acute brain injury: A secondary analysis of the ENIO study".
Authors: Battaglini D; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. Electronic address: denise.battaglini@unige.it., Cinotti R; Department of Anaesthesia and Critical Care, Centre Hospitalier Universitaire de Nantes, Nantes, France., Asehnoune K; Department of Anaesthesia and Critical Care, Centre Hospitalier Universitaire de Nantes, Nantes, France., Loggini A; Brain and Spine Institute, Southern Illinois Healthcare, Carbondale, IL, United States; Southern Illinois University School of Medicine, Carbondale, IL, United States., Montagnani L; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Ball L; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Gualdi F; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Rocco PRM; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Schultz MJ; Department of Clinical Medicine, University of Oxford Nuffield, Oxford, UK; Department of Anaesthesiology, Rescue and Pain Medicine, HOCH Health Ostschweiz, Cantonal Hospital St. Gallen, St. Gallen, Switzerland; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; Department of Anesthesia, General Intensive Care and Pain Management, Division of Cardiothoracic and Vascular Anesthesia & Critical Care Medicine, Medical University of Vienna, Vienna, Austria., Patroniti NA; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Robba C; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Source: Journal of critical care [J Crit Care] 2026 Jun; Vol. 93, pp. 155449. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Letter
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8610642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8615 (Electronic) Linking ISSN: 08839441 NLM ISO Abbreviation: J Crit Care Subsets: MEDLINE; In Process
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  Data: Authors reply: "Associations of positive end-expiratory pressure (PEEP) with extubation failure and clinical outcomes in invasively ventilated patients with acute brain injury: A secondary analysis of the ENIO study".
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  Data: <searchLink fieldCode="AU" term="%22Battaglini+D%22">Battaglini D</searchLink>; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. Electronic address: denise.battaglini@unige.it.<br /><searchLink fieldCode="AU" term="%22Cinotti+R%22">Cinotti R</searchLink>; Department of Anaesthesia and Critical Care, Centre Hospitalier Universitaire de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Asehnoune+K%22">Asehnoune K</searchLink>; Department of Anaesthesia and Critical Care, Centre Hospitalier Universitaire de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Loggini+A%22">Loggini A</searchLink>; Brain and Spine Institute, Southern Illinois Healthcare, Carbondale, IL, United States; Southern Illinois University School of Medicine, Carbondale, IL, United States.<br /><searchLink fieldCode="AU" term="%22Montagnani+L%22">Montagnani L</searchLink>; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Ball+L%22">Ball L</searchLink>; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Gualdi+F%22">Gualdi F</searchLink>; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Rocco+PRM%22">Rocco PRM</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Schultz+MJ%22">Schultz MJ</searchLink>; Department of Clinical Medicine, University of Oxford Nuffield, Oxford, UK; Department of Anaesthesiology, Rescue and Pain Medicine, HOCH Health Ostschweiz, Cantonal Hospital St. Gallen, St. Gallen, Switzerland; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; Department of Anesthesia, General Intensive Care and Pain Management, Division of Cardiothoracic and Vascular Anesthesia & Critical Care Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Patroniti+NA%22">Patroniti NA</searchLink>; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Robba+C%22">Robba C</searchLink>; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Italy; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
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  Data: <searchLink fieldCode="JN" term="%228610642%22">Journal of critical care</searchLink> [J Crit Care] 2026 Jun; Vol. 93, pp. 155449. <i>Date of Electronic Publication: </i>2026 Jan 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8610642 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-8615 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208839441%22">08839441 </searchLink><i>NLM ISO Abbreviation: </i>J Crit Care <i>Subsets: </i>MEDLINE; In Process
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