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Robust SH2 binding affinity indicates minimal SH3-to-SH2 communication in Grb2.

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Title: Robust SH2 binding affinity indicates minimal SH3-to-SH2 communication in Grb2.
Authors: Ventura ES; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy., Di Felice M; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy., Toso J; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy., Pennacchietti V; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy., Toto A; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy., Gianni S; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy. stefano.gianni@uniroma1.it.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy. stefano.gianni@uniroma1.it.
Source: Biology direct [Biol Direct] 2026 Jan 23; Vol. 21 (1), pp. 23. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Robust SH2 binding affinity indicates minimal SH3-to-SH2 communication in Grb2.
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  Data: <searchLink fieldCode="AU" term="%22Ventura+ES%22">Ventura ES</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Felice+M%22">Di Felice M</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Toso+J%22">Toso J</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pennacchietti+V%22">Pennacchietti V</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Toto+A%22">Toto A</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gianni+S%22">Gianni S</searchLink>; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy. stefano.gianni@uniroma1.it.; Fondazione Cenci Bolognetti, Laboratory affiliated to Istituto Pasteur Italia, Rome, Italy. stefano.gianni@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%22101258412%22">Biology direct</searchLink> [Biol Direct] 2026 Jan 23; Vol. 21 (1), pp. 23. <i>Date of Electronic Publication: </i>2026 Jan 23.
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