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Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry.

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Title: Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry.
Authors: Erzingatzian A; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Al-Baldawi Z; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Ruel I; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Brown L; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Sherman MH; Department of Endocrinology, McGill University Health Centre, Montreal, Quebec, Canada., Laflamme N; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada., Bergeron J; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada., Couture P; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada., Paquette M; Lipids, Nutrition, and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Quebec, Canada., Baass A; Lipids, Nutrition, and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Quebec, Canada., Brisson D; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada., Larouche M; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada., Gaudet D; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada., Cermakova L; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Wan D; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Brunham LR; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Francis GA; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Mancini GBJ; Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada., Kennedy BA; Departments of Medicine and Biochemistry, Schulich School of Medicine and Robarts Research Institute, Western University, London, Ontario, Canada., Hegele RA; Departments of Medicine and Biochemistry, Schulich School of Medicine and Robarts Research Institute, Western University, London, Ontario, Canada., Lewis GF; Department of Medicine and Department of Physiology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., McCrindle BW; Department of Pediatrics, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ransom T; Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada., McPherson R; Lipid Clinic & Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Piazza N; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., de Varennes B; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Genest J; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Iatan I; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: Iulia.Iatan@mcgill.ca.
Source: JACC. Advances [JACC Adv] 2026 Feb; Vol. 5 (2), pp. 102505. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918419284106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-963X (Electronic) Linking ISSN: 2772963X NLM ISO Abbreviation: JACC Adv Subsets: PubMed not MEDLINE
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  Data: Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry.
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  Data: <searchLink fieldCode="AU" term="%22Erzingatzian+A%22">Erzingatzian A</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Al-Baldawi+Z%22">Al-Baldawi Z</searchLink>; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ruel+I%22">Ruel I</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Brown+L%22">Brown L</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Sherman+MH%22">Sherman MH</searchLink>; Department of Endocrinology, McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Laflamme+N%22">Laflamme N</searchLink>; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Bergeron+J%22">Bergeron J</searchLink>; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Couture+P%22">Couture P</searchLink>; Endocrinology and Nephrology Unit, CHU de Québec - Université Laval Research Center, Québec City, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Paquette+M%22">Paquette M</searchLink>; Lipids, Nutrition, and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Baass+A%22">Baass A</searchLink>; Lipids, Nutrition, and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Brisson+D%22">Brisson D</searchLink>; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Larouche+M%22">Larouche M</searchLink>; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Gaudet+D%22">Gaudet D</searchLink>; Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Cermakova+L%22">Cermakova L</searchLink>; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Wan+D%22">Wan D</searchLink>; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Brunham+LR%22">Brunham LR</searchLink>; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Francis+GA%22">Francis GA</searchLink>; Centre for Heart Lung Innovation, Providence Health Care Research Institute, Departments of Medicine and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Mancini+GBJ%22">Mancini GBJ</searchLink>; Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Kennedy+BA%22">Kennedy BA</searchLink>; Departments of Medicine and Biochemistry, Schulich School of Medicine and Robarts Research Institute, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hegele+RA%22">Hegele RA</searchLink>; Departments of Medicine and Biochemistry, Schulich School of Medicine and Robarts Research Institute, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lewis+GF%22">Lewis GF</searchLink>; Department of Medicine and Department of Physiology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22McCrindle+BW%22">McCrindle BW</searchLink>; Department of Pediatrics, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ransom+T%22">Ransom T</searchLink>; Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada.<br /><searchLink fieldCode="AU" term="%22McPherson+R%22">McPherson R</searchLink>; Lipid Clinic & Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Piazza+N%22">Piazza N</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22de+Varennes+B%22">de Varennes B</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Genest+J%22">Genest J</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Iatan+I%22">Iatan I</searchLink>; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: Iulia.Iatan@mcgill.ca.
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  Data: <searchLink fieldCode="JN" term="%229918419284106676%22">JACC. Advances</searchLink> [JACC Adv] 2026 Feb; Vol. 5 (2), pp. 102505. <i>Date of Electronic Publication: </i>2026 Jan 23.
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