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Dysregulation of the ALDH1A3/PML-RARα axis promotes the progression of acute promyelocytic leukemia.

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Title: Dysregulation of the ALDH1A3/PML-RARα axis promotes the progression of acute promyelocytic leukemia.
Authors: Cai J; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; Department of Hematology, The General Hospital of Western Theater Command, Chengdu, 610083, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China., Liang CH; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China., Han LP; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China., Jiang HY; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China., Duan JJ; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China., Li F; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China., Liu J; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China., Liang C; Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China., Gao L; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China. Electronic address: gaolei@tmmu.edu.cn., Yu SC; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China. Electronic address: yushicang@tmmu.edu.cn.
Source: Cancer letters [Cancer Lett] 2026 Apr 01; Vol. 642, pp. 218280. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dysregulation of the ALDH1A3/PML-RARα axis promotes the progression of acute promyelocytic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Cai+J%22">Cai J</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; Department of Hematology, The General Hospital of Western Theater Command, Chengdu, 610083, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China.<br /><searchLink fieldCode="AU" term="%22Liang+CH%22">Liang CH</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China.<br /><searchLink fieldCode="AU" term="%22Han+LP%22">Han LP</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China.<br /><searchLink fieldCode="AU" term="%22Jiang+HY%22">Jiang HY</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China.<br /><searchLink fieldCode="AU" term="%22Duan+JJ%22">Duan JJ</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China.<br /><searchLink fieldCode="AU" term="%22Liang+C%22">Liang C</searchLink>; Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Department of Hematology, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing, 400037, China. Electronic address: gaolei@tmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+SC%22">Yu SC</searchLink>; Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing, 400038, China; Jin-feng Laboratory, Chongqing, 401329, China. Electronic address: yushicang@tmmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 Apr 01; Vol. 642, pp. 218280. <i>Date of Electronic Publication: </i>2026 Jan 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.canlet.2026.218280
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        Text: English
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      – TitleFull: Dysregulation of the ALDH1A3/PML-RARα axis promotes the progression of acute promyelocytic leukemia.
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              Text: 2026 Apr 01
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