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let-7c-5p promotes fracture healing by downregulating CDK8.

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Title: let-7c-5p promotes fracture healing by downregulating CDK8.
Authors: Liu W; Department of Orthopedics, Tianjin First Central Hospital, Tianjin, 300192, China., Zhang J; Department of Joint Surgery and Geriatric Orthopedics, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China.; Guangxi Key Laboratory for Preclinical and Translational Research on Bone and Joint Degenerative Diseases, Baise, 533000, China., Chen X; School of Health, Brooks College (Sunnyvale), Sunnyvale, California, 94089, USA.; Department of Epidemiology and Statistics, School of Public Health, Medical College, Zhejiang University, Hangzhou, 310000, China., Cheng B; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China., Li Q; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China., Li L; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China., Yang H; Department of Orthopaedics and Joint Surgery, Affiliated Hospital of Southwest Medical University, No. 8, Section 2, Kangcheng Road, Jiangyang District, Sichuan, 646000, Luzhou, China. hongbinyangd1@163.com.
Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2026 Jan 24; Vol. 21 (1), pp. 134. Date of Electronic Publication: 2026 Jan 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: let-7c-5p promotes fracture healing by downregulating CDK8.
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  Data: <searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Orthopedics, Tianjin First Central Hospital, Tianjin, 300192, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Joint Surgery and Geriatric Orthopedics, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China.; Guangxi Key Laboratory for Preclinical and Translational Research on Bone and Joint Degenerative Diseases, Baise, 533000, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; School of Health, Brooks College (Sunnyvale), Sunnyvale, California, 94089, USA.; Department of Epidemiology and Statistics, School of Public Health, Medical College, Zhejiang University, Hangzhou, 310000, China.<br /><searchLink fieldCode="AU" term="%22Cheng+B%22">Cheng B</searchLink>; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Second Orthopedic Department, Zhangzhou Zhengxing Hospital, Zhangzhou, 363000, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Orthopaedics and Joint Surgery, Affiliated Hospital of Southwest Medical University, No. 8, Section 2, Kangcheng Road, Jiangyang District, Sichuan, 646000, Luzhou, China. hongbinyangd1@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101265112%22">Journal of orthopaedic surgery and research</searchLink> [J Orthop Surg Res] 2026 Jan 24; Vol. 21 (1), pp. 134. <i>Date of Electronic Publication: </i>2026 Jan 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265112 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1749-799X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221749799X%22">1749799X </searchLink><i>NLM ISO Abbreviation: </i>J Orthop Surg Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13018-026-06678-7
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        StartPage: 134
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      – TitleFull: let-7c-5p promotes fracture healing by downregulating CDK8.
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              Text: 2026 Jan 24
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              Y: 2026
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