Residual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.

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Title: Residual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.
Authors: Stewart I; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK. Electronic address: iain.stewart@imperial.ac.uk., Jacob J; Satsuma Lab, Centre for Medical Imaging Computing, University College London, UK; UCL Respiratory, University College London, UK; University College London Hospitals NHS Foundation Trust, UK., Porter JC; UCL Respiratory, University College London, UK; University College London Hospitals NHS Foundation Trust, UK., Liu B; National Heart and Lung Institute, Imperial College London, UK., Tatler AL; School of Medicine, University of Nottingham, UK; NIHR Nottingham Biomedical Research Centre, University of Nottingham, UK., Gomez N; School of Medicine, University of Nottingham, UK; NIHR Nottingham Biomedical Research Centre, University of Nottingham, UK., Pugh MR; Institute of Immunology and Immunotherapy, University of Birmingham, UK., John AE; National Heart and Lung Institute, Imperial College London, UK., Allen RJ; Department of Health Sciences, University of Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Blaikley JF; Manchester University NHS Foundation Trust, UK; School of Biological Sciences, University of Manchester, UK., Chaudhuri N; Ulster University, UK., Denneny E; UCL Respiratory, University College London, UK., Fabbri L; National Heart and Lung Institute, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK., George PM; National Heart and Lung Institute, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK., Guillen-Guio B; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Gooptu B; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Hall IP; School of Medicine, University of Nottingham, UK; NIHR Nottingham Biomedical Research Centre, University of Nottingham, UK., Ho LP; Oxford University Hospitals NHS Foundation Trust, UK; Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, UK., Jarrold I; Asthma + Lung UK, UK., Johnson S; School of Medicine, University of Nottingham, UK., Jones MG; University Hospital Southampton NHS Foundation Trust, UK., Khan F; University Hospitals of Leicester NHS Trust, UK., Mehta P; UCL Respiratory, University College London, UK., Mitchell J; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK., Molyneaux PL; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK., Pearl JE; Department of Respiratory Sciences, University of Leicester, UK., Piper Hanley K; School of Medical Sciences, University of Manchester, UK., Platé M; UCL Respiratory, University College London, UK., Quinn V; National Heart and Lung Institute, Imperial College London, UK., Rivera-Ortega P; Manchester University NHS Foundation Trust, UK., Saunders LC; School of Medicine & Population Health, University of Sheffield, UK., Smith DJF; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK., Spears M; NHS Tayside & University of Dundee, UK., Spencer LG; Liverpool University Hospitals NHS Foundation Trust, UK., Stanel SC; Manchester University NHS Foundation Trust, UK; School of Biological Sciences, University of Manchester, UK., Thompson AAR; School of Medicine & Population Health, University of Sheffield, UK; NIHR Sheffield Biomedical Research Centre, University of Sheffield, UK., Walsh S; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK., Wild JM; School of Medicine & Population Health, University of Sheffield, UK., Wootton DG; Liverpool University Hospitals NHS Foundation Trust, UK., Docherty AB; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, UK., Gleeson F; Oxford University Hospitals NHS Foundation Trust, UK., Greenhalf W; Liverpool University Hospitals NHS Foundation Trust, UK; University of Liverpool, UK., Harrison EM; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, UK., Lone N; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, UK., Quint J; National Heart and Lung Institute, Imperial College London, UK., Maslova A; Sysmex R&D Centre UK, UK., Pohl M; Sysmex R&D Centre UK, UK., Stephens A; Sysmex R&D Centre UK, UK., Young S; Sysmex R&D Centre UK, UK., Singapuri A; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Shikotra A; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Sereno M; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Saunders RM; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Richardson M; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Raman B; Oxford University Hospitals NHS Foundation Trust, UK., Poinasamy K; Asthma + Lung UK, UK., McAuley HJC; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Marks M; London School of Hygiene & Tropical Medicine, UK., Leavy OC; Department of Health Sciences, University of Leicester, UK., Houchen-Wolloff L; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Horsley A; Manchester University NHS Foundation Trust, UK., Harris VC; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Greening N; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Evans RA; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Elneima O; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Chalmers JD; NHS Tayside & University of Dundee, UK., Brightling CE; NIHR Leicester Biomedical Research Centre, University of Leicester, UK; School of Biological Sciences, University of Manchester, UK; University Hospitals of Leicester NHS Trust, UK., Chambers RC; UCL Respiratory, University College London, UK., Wain LV; Department of Health Sciences, University of Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, UK., Jenkins RG; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK.
Corporate Authors: PHOSP-COVID Collaborative Group and the UKILD Consortium
Source: EBioMedicine [EBioMedicine] 2026 Feb; Vol. 124, pp. 106134. Date of Electronic Publication: 2026 Jan 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Residual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.
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  Data: <searchLink fieldCode="AU" term="%22Stewart+I%22">Stewart I</searchLink>; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK. 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Institute of Immunology and Immunotherapy, University of Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22John+AE%22">John AE</searchLink>; National Heart and Lung Institute, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Allen+RJ%22">Allen RJ</searchLink>; Department of Health Sciences, University of Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Blaikley+JF%22">Blaikley JF</searchLink>; Manchester University NHS Foundation Trust, UK; School of Biological Sciences, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+N%22">Chaudhuri N</searchLink>; Ulster University, UK.<br /><searchLink fieldCode="AU" term="%22Denneny+E%22">Denneny E</searchLink>; UCL Respiratory, University College London, UK.<br /><searchLink fieldCode="AU" term="%22Fabbri+L%22">Fabbri L</searchLink>; National Heart and Lung Institute, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22George+PM%22">George PM</searchLink>; National Heart and Lung Institute, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Guillen-Guio+B%22">Guillen-Guio B</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Gooptu+B%22">Gooptu B</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Hall+IP%22">Hall IP</searchLink>; School of Medicine, University of Nottingham, UK; NIHR Nottingham Biomedical Research Centre, University of Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Ho+LP%22">Ho LP</searchLink>; Oxford University Hospitals NHS Foundation Trust, UK; Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jarrold+I%22">Jarrold I</searchLink>; Asthma + Lung UK, UK.<br /><searchLink fieldCode="AU" term="%22Johnson+S%22">Johnson S</searchLink>; School of Medicine, University of Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Jones+MG%22">Jones MG</searchLink>; University Hospital Southampton NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Khan+F%22">Khan F</searchLink>; University Hospitals of Leicester NHS Trust, UK.<br /><searchLink fieldCode="AU" term="%22Mehta+P%22">Mehta P</searchLink>; UCL Respiratory, University College London, UK.<br /><searchLink fieldCode="AU" term="%22Mitchell+J%22">Mitchell J</searchLink>; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Molyneaux+PL%22">Molyneaux PL</searchLink>; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Pearl+JE%22">Pearl JE</searchLink>; Department of Respiratory Sciences, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Piper+Hanley+K%22">Piper Hanley K</searchLink>; School of Medical Sciences, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Platé+M%22">Platé M</searchLink>; UCL Respiratory, University College London, UK.<br /><searchLink fieldCode="AU" term="%22Quinn+V%22">Quinn V</searchLink>; National Heart and Lung Institute, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Rivera-Ortega+P%22">Rivera-Ortega P</searchLink>; Manchester University NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Saunders+LC%22">Saunders LC</searchLink>; School of Medicine & Population Health, University of Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Smith+DJF%22">Smith DJF</searchLink>; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Spears+M%22">Spears M</searchLink>; NHS Tayside & University of Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Spencer+LG%22">Spencer LG</searchLink>; Liverpool University Hospitals NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Stanel+SC%22">Stanel SC</searchLink>; Manchester University NHS Foundation Trust, UK; School of Biological Sciences, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Thompson+AAR%22">Thompson AAR</searchLink>; School of Medicine & Population Health, University of Sheffield, UK; NIHR Sheffield Biomedical Research Centre, University of Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Walsh+S%22">Walsh S</searchLink>; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Wild+JM%22">Wild JM</searchLink>; School of Medicine & Population Health, University of Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Wootton+DG%22">Wootton DG</searchLink>; Liverpool University Hospitals NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Docherty+AB%22">Docherty AB</searchLink>; 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NIHR Leicester Biomedical Research Centre, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Jenkins+RG%22">Jenkins RG</searchLink>; National Heart and Lung Institute, Imperial College London, UK; NIHR Imperial Biomedical Research Centre, Imperial College London, UK; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, UK.
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            NameFull: Richardson M
      – PersonEntity:
          Name:
            NameFull: Raman B
      – PersonEntity:
          Name:
            NameFull: Poinasamy K
      – PersonEntity:
          Name:
            NameFull: McAuley HJC
      – PersonEntity:
          Name:
            NameFull: Marks M
      – PersonEntity:
          Name:
            NameFull: Leavy OC
      – PersonEntity:
          Name:
            NameFull: Houchen-Wolloff L
      – PersonEntity:
          Name:
            NameFull: Horsley A
      – PersonEntity:
          Name:
            NameFull: Harris VC
      – PersonEntity:
          Name:
            NameFull: Greening N
      – PersonEntity:
          Name:
            NameFull: Evans RA
      – PersonEntity:
          Name:
            NameFull: Elneima O
      – PersonEntity:
          Name:
            NameFull: Chalmers JD
      – PersonEntity:
          Name:
            NameFull: Brightling CE
      – PersonEntity:
          Name:
            NameFull: Chambers RC
      – PersonEntity:
          Name:
            NameFull: Wain LV
      – PersonEntity:
          Name:
            NameFull: Jenkins RG
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2352-3964
          Numbering:
            – Type: volume
              Value: 124
          Titles:
            – TitleFull: EBioMedicine
              Type: main
ResultId 1