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Paramagnetic Rim Lesions and Development of Clinical MS in Radiologically Isolated Syndrome.

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Title: Paramagnetic Rim Lesions and Development of Clinical MS in Radiologically Isolated Syndrome.
Authors: Lim TR; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Suthiphosuwan S; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Gaitán MI; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland., Marrodán M; Department of Neurology, Fleni, Buenos Aires, Argentina., Horwath EA; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia., Guenette M; Division of Neurology, Department of Medicine, St Michael's Hospital BARLO MS Centre, University of Toronto, Toronto, Ontario, Canada., Bharatha A; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Sati P; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California., Absinta M; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Experimental Neuropathology Lab, IRCCS Humanitas Research Hospital, Milan, Italy., Correale J; Department of Neurology, Fleni, Buenos Aires, Argentina.; Institute of Biological Chemistry and Biophysics (IQUIFIB), CONICET, University of Buenos Aires, Buenos Aires, Argentina., Shinohara RT; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia.; Center for AI and Data Science for Integrated Diagnostics, University of Pennsylvania Perelman School of Medicine, Philadelphia., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland., Oh J; Division of Neurology, Department of Medicine, St Michael's Hospital BARLO MS Centre, University of Toronto, Toronto, Ontario, Canada.
Source: JAMA neurology [JAMA Neurol] 2026 Mar 01; Vol. 83 (3), pp. 250-258.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Paramagnetic Rim Lesions and Development of Clinical MS in Radiologically Isolated Syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Lim+TR%22">Lim TR</searchLink>; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Suthiphosuwan+S%22">Suthiphosuwan S</searchLink>; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Gaitán+MI%22">Gaitán MI</searchLink>; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Marrodán+M%22">Marrodán M</searchLink>; Department of Neurology, Fleni, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Horwath+EA%22">Horwath EA</searchLink>; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Guenette+M%22">Guenette M</searchLink>; Division of Neurology, Department of Medicine, St Michael's Hospital BARLO MS Centre, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Bharatha+A%22">Bharatha A</searchLink>; Division of Neuroradiology, Department of Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sati+P%22">Sati P</searchLink>; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Absinta+M%22">Absinta M</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Experimental Neuropathology Lab, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Correale+J%22">Correale J</searchLink>; Department of Neurology, Fleni, Buenos Aires, Argentina.; Institute of Biological Chemistry and Biophysics (IQUIFIB), CONICET, University of Buenos Aires, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Shinohara+RT%22">Shinohara RT</searchLink>; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia.; Center for AI and Data Science for Integrated Diagnostics, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Reich+DS%22">Reich DS</searchLink>; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Oh+J%22">Oh J</searchLink>; Division of Neurology, Department of Medicine, St Michael's Hospital BARLO MS Centre, University of Toronto, Toronto, Ontario, Canada.
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