View in EDS

Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR.

Saved in:
Bibliographic Details
Title: Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR.
Authors: Portier I; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Denorme F; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Tolley ND; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Kosaka Y; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Andrianova I; Department of Emergency Medicine, Washington University, St Louis, MO., Sigala PA; Department of Biochemistry, University of Utah, Salt Lake City, UT., Lamb TJ; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT., Zimmerman GA; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT., Castro-Faria-Neto HC; Laboratorio de Imunofarmacologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil., Morrell CN; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY., Rondina MT; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT.; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, The University of Utah, Salt Lake City, UT.; Department of Internal Medicine and Geriatric Research, Education, and Clinical Center, George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT., Campbell RA; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.
Source: Blood [Blood] 2026 May 14; Vol. 147 (20), pp. 2388-2401.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41587053
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Portier+I%22">Portier I</searchLink>; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Denorme+F%22">Denorme F</searchLink>; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Tolley+ND%22">Tolley ND</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Kosaka+Y%22">Kosaka Y</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Andrianova+I%22">Andrianova I</searchLink>; Department of Emergency Medicine, Washington University, St Louis, MO.<br /><searchLink fieldCode="AU" term="%22Sigala+PA%22">Sigala PA</searchLink>; Department of Biochemistry, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Lamb+TJ%22">Lamb TJ</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Zimmerman+GA%22">Zimmerman GA</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Castro-Faria-Neto+HC%22">Castro-Faria-Neto HC</searchLink>; Laboratorio de Imunofarmacologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Morrell+CN%22">Morrell CN</searchLink>; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Rondina+MT%22">Rondina MT</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT.; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, The University of Utah, Salt Lake City, UT.; Department of Internal Medicine and Geriatric Research, Education, and Clinical Center, George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Campbell+RA%22">Campbell RA</searchLink>; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2026 May 14; Vol. 147 (20), pp. 2388-2401.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41587053
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1182/blood.2025030841
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2388
    Titles:
      – TitleFull: Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Portier I
      – PersonEntity:
          Name:
            NameFull: Denorme F
      – PersonEntity:
          Name:
            NameFull: Tolley ND
      – PersonEntity:
          Name:
            NameFull: Kosaka Y
      – PersonEntity:
          Name:
            NameFull: Andrianova I
      – PersonEntity:
          Name:
            NameFull: Sigala PA
      – PersonEntity:
          Name:
            NameFull: Lamb TJ
      – PersonEntity:
          Name:
            NameFull: Zimmerman GA
      – PersonEntity:
          Name:
            NameFull: Castro-Faria-Neto HC
      – PersonEntity:
          Name:
            NameFull: Morrell CN
      – PersonEntity:
          Name:
            NameFull: Rondina MT
      – PersonEntity:
          Name:
            NameFull: Campbell RA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 14
              M: 05
              Text: 2026 May 14
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1528-0020
          Numbering:
            – Type: volume
              Value: 147
            – Type: issue
              Value: 20
          Titles:
            – TitleFull: Blood
              Type: main
ResultId 1