Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR.
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| Title: | Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR. |
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| Authors: | Portier I; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Denorme F; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Tolley ND; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Kosaka Y; Molecular Medicine Program, University of Utah, Salt Lake City, UT., Andrianova I; Department of Emergency Medicine, Washington University, St Louis, MO., Sigala PA; Department of Biochemistry, University of Utah, Salt Lake City, UT., Lamb TJ; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT., Zimmerman GA; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT., Castro-Faria-Neto HC; Laboratorio de Imunofarmacologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil., Morrell CN; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY., Rondina MT; Molecular Medicine Program, University of Utah, Salt Lake City, UT.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT.; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, The University of Utah, Salt Lake City, UT.; Department of Internal Medicine and Geriatric Research, Education, and Clinical Center, George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT., Campbell RA; Department of Emergency Medicine, Washington University, St Louis, MO.; Molecular Medicine Program, University of Utah, Salt Lake City, UT. |
| Source: | Blood [Blood] 2026 May 14; Vol. 147 (20), pp. 2388-2401. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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