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IAP Antagonists Selectively Eliminate Therapy-Induced Senescent Cancer Cells via TNFα-Independent Apoptosis.

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Title: IAP Antagonists Selectively Eliminate Therapy-Induced Senescent Cancer Cells via TNFα-Independent Apoptosis.
Authors: Ochiiwa H; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan., Wakasa T; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan., Kataoka Y; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan., Ando K; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Oki E; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Advanced Medicine and Innovative Technology, Kyushu University Hospital, Fukuoka, Japan., Maehara Y; Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan., Iimori M; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan., Kitao H; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan.
Source: Cancer science [Cancer Sci] 2026 Apr; Vol. 117 (4), pp. 1043-1056. Date of Electronic Publication: 2026 Jan 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IAP Antagonists Selectively Eliminate Therapy-Induced Senescent Cancer Cells via TNFα-Independent Apoptosis.
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  Data: <searchLink fieldCode="AU" term="%22Ochiiwa+H%22">Ochiiwa H</searchLink>; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Wakasa+T%22">Wakasa T</searchLink>; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kataoka+Y%22">Kataoka Y</searchLink>; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Taiho Pharmaceutical Co. Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ando+K%22">Ando K</searchLink>; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Oki+E%22">Oki E</searchLink>; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Advanced Medicine and Innovative Technology, Kyushu University Hospital, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Maehara+Y%22">Maehara Y</searchLink>; Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Iimori+M%22">Iimori M</searchLink>; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kitao+H%22">Kitao H</searchLink>; Department of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101168776%22">Cancer science</searchLink> [Cancer Sci] 2026 Apr; Vol. 117 (4), pp. 1043-1056. <i>Date of Electronic Publication: </i>2026 Jan 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+Publishing+on+behalf+of+the+Japanese+Cancer+Association%22">Wiley Publishing on behalf of the Japanese Cancer Association </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101168776 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1349-7006 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213479032%22">13479032 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1111/cas.70329
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        Text: English
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      – TitleFull: IAP Antagonists Selectively Eliminate Therapy-Induced Senescent Cancer Cells via TNFα-Independent Apoptosis.
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              Text: 2026 Apr
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