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Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design.

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Title: Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design.
Authors: Motazedian P; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada., Di Santo P; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada., Prosperi-Porta G; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Nelson D; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Morgan B; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Ratelle C; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Feagan H; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Koopman Z; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Jung R; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Mathieu ME; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Knoll W; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Parlow S; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Abdel-Razek O; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Mathew R; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Wells GA; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada., Chiu MH; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada; Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada., Ballantyne B; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Hibbert B; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Ramirez FD; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: dramirez@ottawaheart.ca.
Source: American heart journal [Am Heart J] 2026 May; Vol. 295, pp. 107358. Date of Electronic Publication: 2026 Jan 25.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design.
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  Data: <searchLink fieldCode="AU" term="%22Motazedian+P%22">Motazedian P</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Di+Santo+P%22">Di Santo P</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Prosperi-Porta+G%22">Prosperi-Porta G</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Nelson+D%22">Nelson D</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Morgan+B%22">Morgan B</searchLink>; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ratelle+C%22">Ratelle C</searchLink>; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Feagan+H%22">Feagan H</searchLink>; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Koopman+Z%22">Koopman Z</searchLink>; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Jung+R%22">Jung R</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Mathieu+ME%22">Mathieu ME</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Knoll+W%22">Knoll W</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Parlow+S%22">Parlow S</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Abdel-Razek+O%22">Abdel-Razek O</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Mathew+R%22">Mathew R</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Wells+GA%22">Wells GA</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chiu+MH%22">Chiu MH</searchLink>; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada; Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ballantyne+B%22">Ballantyne B</searchLink>; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Hibbert+B%22">Hibbert B</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Ramirez+FD%22">Ramirez FD</searchLink>; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Capital Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: dramirez@ottawaheart.ca.
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  Data: <searchLink fieldCode="JN" term="%220370465%22">American heart journal</searchLink> [Am Heart J] 2026 May; Vol. 295, pp. 107358. <i>Date of Electronic Publication: </i>2026 Jan 25.
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  Data: Journal Article; Clinical Trial Protocol
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370465 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200028703%22">00028703 </searchLink><i>NLM ISO Abbreviation: </i>Am Heart J <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ahj.2026.107358
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        Text: English
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